Hoatlin Lab: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
(76 intermediate revisions by 4 users not shown)
Line 1: Line 1:
=Welcome to the Hoatlin Lab Wiki=
{{HoatlinLab}}


Our lab is interested in understanding how the [http://www.fanconi.org/ Fanconi anemia] proteins contribute to genomic stability with the goal of developing drugs that will help Fanconi patients and those who are susceptible to developing cancer.
<div style="padding: 15px; width: 710px; border: 5px solid #B3CD4E;">
We work in [[Hoatlin:Portland Oregon| Portland, Oregon]] at [http://www.ohsu.edu/ OHSU], in the [http://www.ohsu.edu/biochem/ Department of Biochemistry & Molecular Biology]. Our Departmental web pages (not updated wiki-frequently) can be viewed [http://www.ohsu.edu/research/hoatlin/ here (web page)] and [http://www.ohsu.edu/biochem/faculty/faculty.cfm?facultyID=29 here (faculty page)].
<div style="padding: 1px; width: 700px; border: 3px solid #DDDDFF;">


We hope that other Fanconi labs will join us at [http://openwetware.org/wiki/ OpenWetWare] because it might help FA research go faster, stimulate collaborative efforts, facilitate reagent distribution, and expand communication. We also believe that an understanding of the complex and enigmatic Fanconi anemia protein network could benefit from the attention of systems/synthetic biologists already on OWW.  
<div style="border:1px solid orange;background-color:#FFFACD;padding:1px;">
----
'''Lab News'''
;For news, follow the [http://twitter.com/HoatlinLab Hoatlin lab Twitter]
</div>
<br>
Our laboratory is interested in understanding the molecular function of the Fanconi anemia (FA) protein network in context with other proteins that regulate or influence genomic stability. Fanconi anemia is a rare genetic disease that is typically associated with developmental abnormalities, bone marrow failure and increased risk of cancer. Because the majority of the FA proteins are unique with no significant homologies, we expect the results of our studies to shed new light on fundamental mechanisms that control the integrity of the human genome and influence cancer susceptibility. The FA pathway is part of a network of proteins that contains BRCA2 and two other recently identified FA genes (FANCN and FANCJ) that influence breast cancer susceptibility.  Ultimately, insights into the mechanism of the FA/BRCA network of proteins will lead to an understanding of the underlying molecular defect in FA and may lead to more effective avenues of treatment for this devastating pediatric disease and cancer.  


[[Image:Labphoto.JPG|700px|thumb|right|Stacie Stone, Alex Sobeck, Igor Landis, Maureen Hoatlin, Alexis LaChapelle, Hanna Cho, and Victor Wong. Summer, 2007]]
We work in [[Hoatlin:Portland Oregon| Portland, Oregon]] at [http://www.ohsu.edu/ OHSU], in the [http://www.ohsu.edu/biochem/ Department of Biochemistry & Molecular Biology] and the [http://www.ohsucancer.com/ OHSU Knight Cancer Institute].
*[[Hoatlin:Research Interests|Research Interests]]
*[[Hoatlin:Research Team|Research Team]]
*[[Hoatlin:Publications|Publications]]
*[[Hoatlin:Projects|Projects]]
*[[Hoatlin:Fanconi Genes|Fanconi Genes]]
*[[Hoatlin:Collaborations|Collaborations]]
*[[Hoatlin:Reagent Requests|Reagent Requests]]
*[[Hoatlin:Protocols|Standard Protocols]]
*[[Hoatlin:Contact Info|Contact Info & Directions]]
*[[Hoatlin:Contribute|Contribute to FA Research]]
*[[Hoatlin:News|Hoatlin Lab News]]
*[[Hoatlin: View from our Lab|Our View]]
'''*[[Hoatlin:Internal Lab Site|The Back Door]]'''


==OHSU DNA R3 Club==
==Teaching Links==
[[Hoatlin:OHSU Replication, Recombination and Repair (R3) Club| 2006-2007 OHSU DNA Replication, Recombination and Repair (R3) Club]].


==BMB Seminar Series==
*Our lab's Fanconi Anemia antibodies are available from [http://www.novusbio.com Novus Biologicals] and soon by Millipore.


[[Hoatlin:BMB Seminar Series| BMB Seminar Series for 2006-2007]]  
[http://openwetware.org/wiki/CANB_610 Advanced Topics in Cancer Biology (CANB 610)]


[[Hoatlin:BMB Seminar Series '07-'08| BMB Seminar Series for 2007-2008 ]]
[[Hoatlin:OHSU_Genetic_Mechanisms_Class| Genetic Mechanisms Class (CON662)]]


==Biochemistry Courses and Curriculum Development==
[[Hoatlin:OHSU Replication, Recombination and Repair (R3) Club| OHSU DNA Replication, Recombination and Repair (R3) Club]].


[[Hoatlin: CSF|Med Students Cell Structure Function (CSF)]]
==Classes of the past==
[[BMCB625|Advanced Topics in Molecular Biology(BMB625)]]
[[BMCB625|Advanced Topics in Molecular Biology(BMB625)]]
[[Hoatlin:Courses and Curriculum Development|Course List and Course Development Discussion]]
==Volcano, Tram and Nest Cams==
[http://www.kgw.com/livecams/content.html?livecams_OHSU Campus Tram Cam]
[http://www.fs.fed.us/gpnf/volcanocams/msh/ Volcano Cam]
[http://www2.ucsc.edu/scpbrg/falconcameraSJ.htm Peregrine Falcon Nest Cam]-they have fledged! Check out the video archives.


==Who is Visiting Us?==
==Who is Visiting Us?==
Line 51: Line 37:
</a>
</a>
</html>
</html>
[[Image:Hoatlinclustermap.jpg]]
==Basic Wiki/OWW Links==
*[http://openwetware.org/wiki/Help:Contents Help Overview]
*[[OpenWetWare:How_to_join | How to join]]
*[[OWW.101:OpenWetWare | Using OpenWetWare]]


*[[OWW.101:Guidelines for editing OpenWetWare|Guidelines for editing OpenWetWare]]


''[[Simple_wiki_editing_examples|wiki edit instructions]]
<wikionly>
<font size=4>'''Recent changes'''</font>{{Special:Recentchanges/Hoatlin}}
</wikionly>

Revision as of 18:41, 22 January 2014

Equipped with his five senses, man explores the universe around him and calls the adventure Science. ~Edwin Powell Hubble, The Nature of Science, 1954

Home        Projects        Team        Papers        Contact Us        Protocols        Collaborations        News        Reagent Requests        secret back door        Hoatlin Lab Twitter       


Lab News

For news, follow the Hoatlin lab Twitter


Our laboratory is interested in understanding the molecular function of the Fanconi anemia (FA) protein network in context with other proteins that regulate or influence genomic stability. Fanconi anemia is a rare genetic disease that is typically associated with developmental abnormalities, bone marrow failure and increased risk of cancer. Because the majority of the FA proteins are unique with no significant homologies, we expect the results of our studies to shed new light on fundamental mechanisms that control the integrity of the human genome and influence cancer susceptibility. The FA pathway is part of a network of proteins that contains BRCA2 and two other recently identified FA genes (FANCN and FANCJ) that influence breast cancer susceptibility. Ultimately, insights into the mechanism of the FA/BRCA network of proteins will lead to an understanding of the underlying molecular defect in FA and may lead to more effective avenues of treatment for this devastating pediatric disease and cancer.

We work in Portland, Oregon at OHSU, in the Department of Biochemistry & Molecular Biology and the OHSU Knight Cancer Institute.

Teaching Links

  • Our lab's Fanconi Anemia antibodies are available from Novus Biologicals and soon by Millipore.

Advanced Topics in Cancer Biology (CANB 610)

Genetic Mechanisms Class (CON662)

OHSU DNA Replication, Recombination and Repair (R3) Club.

Med Students Cell Structure Function (CSF)

Classes of the past

Advanced Topics in Molecular Biology(BMB625)

Who is Visiting Us?

Who's visiting?

<html> <a href="http://clustrmaps.com/counter/maps.php?url=http://openwetware.org/wiki/Hoatlin_Lab" id="clustrMapsLink"><img src="http://clustrmaps.com/counter/index2.php?url=http://openwetware.org/wiki/Hoatlin_Lab" border=1 alt="Locations of visitors to this page"onError="this.onError=null; this.src='http://www.meetomatic.com/images/clustrmaps-back-soon.jpg'; document.getElementById('clustrMapsLink').href='http://clustrmaps.com/'"> </a> </html>

Basic Wiki/OWW Links

<wikionly>

Recent changes
List of abbreviations:
N
This edit created a new page (also see list of new pages)
m
This is a minor edit
b
This edit was performed by a bot
(±123)
The page size changed by this number of bytes

14 June 2024

 N    12:55  UA Biophysics:Peptides and IA‎‎ 3 changes history +1,837‎ [Elizabeth Suesca‎ (3×)]
     
12:55 (cur | prev) +44‎ Elizabeth Suesca talk contribs
     
12:54 (cur | prev) −68‎ Elizabeth Suesca talk contribs
N    
12:45 (cur | prev) +1,861‎ Elizabeth Suesca talk contribs (Created page with "Debido a la rápida aparición de mecanismos de resistencia a antibióticos en diferentes microorganismos patógenos potencialmente mortales a nivel mundial, existe un gran interés en la identificación de agentes antimicrobianos alternativos que puedan ayudar en el desarrollo de nuevas estrategias de tratamiento. Mediante la aplicación de una rutina de Deep Learning, desarrollada y publicada por el grupo de investigación proponente, se predecirá una lista de candida...")
     12:45  Biophysics‎‎ 3 changes history +204‎ [Elizabeth Suesca‎ (3×)]
     
12:45 (cur | prev) +4‎ Elizabeth Suesca talk contribs
     
12:44 (cur | prev) +1‎ Elizabeth Suesca talk contribs
     
12:29 (cur | prev) +199‎ Elizabeth Suesca talk contribs

13 June 2024

     14:39 User creation log User account Yannvrb talk contribs was created by Yar talk contribs and password was sent by email ‎
     13:57  Magni:Back Door‎‎ 2 changes history +199‎ [Lorenzo Pasotti‎ (2×)]
     
13:57 (cur | prev) +151‎ Lorenzo Pasotti talk contribs
     
13:54 (cur | prev) +48‎ Lorenzo Pasotti talk contribs (→‎E. coli strains)
     08:28  WAKNA:Basics‎‎ 3 changes history −73‎ [Berthold Drexler‎ (3×)]
     
08:28 (cur | prev) −204‎ Berthold Drexler talk contribs (→‎Hier finden Sie Literatur für Einsteiger:innen in das Gebiet der Neuroanästhesie)
     
08:26 (cur | prev) 0‎ Berthold Drexler talk contribs (→‎Hier finden Sie Literatur für Einsteiger:innen in das Gebiet der Neuroanästhesie)
     
08:26 (cur | prev) +131‎ Berthold Drexler talk contribs (→‎halbsitzende Lagerung und Luftembolie)

12 June 2024

 N    13:10  Karas Lab:YAEL Electrode Localization‎‎ 2 changes history +859‎ [Aclesage‎ (2×)]
     
13:10 (cur | prev) +585‎ Aclesage talk contribs
N    
13:08 (cur | prev) +274‎ Aclesage talk contribs (Created page with "<b>Y</b>our <b>A</b>dvanced <b>E</b>lectrode <b>L</b>ocalizer (YAEL) is free and open-source software for localizing and visualizing electrodes. YAEL is a sister package to the RAVE software toolbox for the analysis of intracranial electroencephalogram (iEEG) data.")
     13:04  Karas Lab:Lab Notebook‎‎ 2 changes history +48‎ [Aclesage‎ (2×)]
     
13:04 (cur | prev) 0‎ Aclesage talk contribs
     
13:00 (cur | prev) +48‎ Aclesage talk contribs
     06:13  Hu:Publications‎ diffhist +33‎ Hugangqing talk contribs
     06:12  Hu‎ diffhist +44‎ Hugangqing talk contribs

11 June 2024

N    19:16  BioMicroCenter:PricingFY2025‎ diffhist +28,119‎ Stuart S. Levine talk contribs (Created page with "''' PRICING UPDATE 7/1/2024 ''' == SEQUENCING == Please note that samples submitted from '''CORE LAB'''s will be given priority on all equipment. The BioMicro Center reserves the right to reject samples for any reason. <BR><BR> === NOVASEQ SEQUENCING === {| class="wikitable" border=1  ! NOVASEQ SEQUENCING !width=80| CORE LAB !width=80| MIT !width=80| Non-MIT !width=80| uni...")
     18:40  BioMicroCenter:Pricing‎ diffhist +54‎ Stuart S. Levine talk contribs (→‎COMPUTATIONAL SERVICES)
      08:18  Forster Lab‎‎ 2 changes history +153‎ [Anthony C. Forster‎ (2×)]
 m   
08:18 (cur | prev) +4‎ Anthony C. Forster talk contribs (→‎The Boss!?)
     
08:16 (cur | prev) +149‎ Anthony C. Forster talk contribs (→‎The Boss!?)
     08:03  Pecreaux‎ diffhist −1,628‎ Cedre-PecreauxLab talk contribs (→‎News!)

</wikionly>

Retrieved from "https://openwetware.org/mediawiki/index.php?title=Hoatlin_Lab&oldid=765854"