The Mutants Research Project Week 14

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Mutants Week 14 group journal

The Mutants Week 14


Final Presentation Slides

Acknolwdgements

  • I spoke with my partners, Macie M. Duran, JT Correy, and Fatimah Alghanem over Zoom and text to discuss our journal article and plan our presentation.
  • I copied and modified the procedures shown on the Week 14 assignment page.
  • I acknowledge my professor, Kam D. Dahlquist, Ph.D., with whom I met several times via zoom to discuss questions regarding the purpose and format.
  • I acknowledge my TA, Annika Dinulos, whom I contacted regarding a question for one of my assignments.
  • GenBank was used to obtain spike protein sequences for multiple sequence alignment.
  • The GISAID database was used to track the prevalence of G614 in the United States over time.

Except for what is noted above, this individual journal entry was completed by me and not copied from another source. Yaniv Maddahi (talk) 10:03, 9 December 2020 (PST)

References

  • Korber, B., Fischer, W. M., Gnanakaran, S., Yoon, H., Theiler, J., Abfalterer, W., ... & Hastie, K. M. (2020). Tracking changes in SARS-CoV-2 Spike: evidence that D614G increases infectivity of the COVID-19 virus. Cell, 182(4), 812-827.
  • Fernández, A. (2020). Structural impact of mutation D614G in SARS-CoV-2 spike protein: enhanced infectivity and therapeutic opportunity. ACS medicinal chemistry letters, 11(9), 1667-1670.
  • Leung, K., Pei, Y., Leung, G. M., Lam, T. T., & Wu, J. T. (2020). Empirical transmission advantage of the D614G mutant strain of SARS-CoV-2. medRxiv.
  • OpenWetWare. (2020). BIOL368/F20:Week 12. Retrieved 2 December 2020, from https://openwetware.org/wiki/BIOL368/F20:Week_12
  • Wrapp, D., Wang, N., Corbett, K. S., Goldsmith, J. A., Hsieh, C., Abiona, O., . . . Mclellan, J. S. (2020). Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science, 367(6483), 1260-1263. doi:10.1126/science.abb2507
  • Becerra‐Flores, M., & Cardozo, T. (2020). SARS‐CoV‐2 viral spike G614 mutation exhibits higher case fatality rate. International Journal of Clinical Practice.
  • Korber, B., Fischer, W. M., Gnanakaran, S., Yoon, H., Theiler, J., Abfalterer, W., ... & Hastie, K. M. (2020). Tracking changes in SARS-CoV-2 Spike: evidence that D614G increases infectivity of the COVID-19 virus. Cell, 182(4), 812-827.
  • Leung, K., Pei, Y., Leung, G. M., Lam, T. T., & Wu, J. T. (2020). Empirical transmission advantage of the D614G mutant strain of SARS-CoV-2. medRxiv.
  • Nextstrain. (2020). Genomic epidemiology of novel coronavirus - North America-focused subsampling. https://nextstrain.org
  • Wrapp, D., Wang, N., Corbett, K. S., Goldsmith, J. A., Hsieh, C., Abiona, O., . . . Mclellan, J. S. (2020). Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science, 367(6483), 1260-1263. doi:10.1126/science.abb2507


Yaniv Maddahi Template

BIOL368/F20

Yaniv Maddahi

Yaniv Maddahi Template

Assignment Week

Individual Journal Pages

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