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[[Image:ltp.jpg]] | [[Image:ltp.jpg]] | ||
Figure 3. AMPARs are inserted during LTP in hippocampal neurons in culture. Surface-expressed AMPARs on a living cultured hippocampal neuron detected using antibodies directed against AMPAR before (top) and after (middle) induction of NMDAR-dependent LTP in culture. Colocalisation is shown in the bottom panel, red puncta are new AMPARs inserted during LTP. | |||
After the early phase of LTP (E-LTP) in which these pre- and post-synaptic changes occur, the late phase (L-LTP) can lead to the formation of new synapses. | After the early phase of LTP (E-LTP) in which these pre- and post-synaptic changes occur, the late phase (L-LTP) can lead to the formation of new synapses. |
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