BIO254:Silent: Difference between revisions

BIO254:Silent (view source)

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 ==NMDA receptors (NMDAR)==
-NMDA receptors additionally require postsynaptic depolarization to eject a Mg^{2+} ion that blocks the channel during normal operation. As a result, the relative contribution of NMDA receptors to the EPSC depends on the postsynaptic membrane potential.
+NMDA receptors additionally require postsynaptic depolarization to eject a Mg<sup>2+</sup> ion that blocks the channel during normal operation. As a result, the relative contribution of NMDA receptors to the EPSC depends on the postsynaptic membrane potential.
-Also unlike AMPA receptors, open NMDA receptors permit the influx of Ca^{2+}, which plays a role in LTP (see below).
+Also unlike AMPA receptors, open NMDA receptors permit the influx of Ca<sup>2+</sup>, which plays a role in LTP (see below).
 The inactivity of an NMDA-only synapse when the postsynaptic cell is polarized below -40 mV gives the silent synapse its name.