Harvard:Biophysics 242r/2011

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Biophysics 242r/2011

Biologically Inspired Molecular Engineering

DNA nanostructure logo 2010-10-23.png

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Course overview

  • Graduate level seminar focusing on in-silico design pipelines for nucleic acid- and protein-based molecular machinery and programmable molecular systems. Students are mentored to produce substantial midterm and final group design projects.
  • No formal prerequisites. Projects are tailored to each student's strengths and interests.


Example topics for final design project

  • Artificial chemotactic swimmers
  • Nonequilibrium networks of nano-machines mimicking dynamic instability in the cytoskeleton
  • Nucleic acid logic automata responsive to microRNAs in serum
  • Self-assembled solar energy harvester based on bio-inorganic nano-antennae for uv-vis
  • Systematic debugging of DNA labeling chemistries by atomic-resolution TEM imaging of DNA origami
  • Light-controlled transcriptional activation and repression through rational molecular design
  • Directed evolution of tissue engineering scaffold nano-materials
  • Programmable multistep chemical synthesis by templating on nanostructures
  • Ultra-sensitive molecular signal processing for synthetic biology
  • Synthetic nanostructure - virus conjugates
  • Nano-breadboards for probing electron transport in proteins
  • Replication of information in synthetic crystals
  • Etc.


Logistics

  • Meeting time: 2011 Spring Term, Mondays and Wednesdays, 100 pm — 230 pm, with optional sessions for working on projects from 230 pm to 330 pm, starting on Monday, February 7
  • Form teams for midterm projects on Monday, February 7
  • Form teams for final projects on Monday, March 21
  • First class on Monday, January 24
  • Location: CLSB521
  • No exams
  • Prerequisites: none
  • Grading
    • 33% Participation
    • 33% Midterm project
    • 33% Final project
  • Harvard course site
  • Harvard:Biophysics_242r/2011/Course Development Log


Background Info and previous class projects


Recent changes

16 August 2018

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(Upload log). .

[Peisheng Xu‎ (3×)]

     

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Xu lab:Lab Members‎‎ (2 changes | history) . . (+115). . [Peisheng Xu‎ (2×)]

     

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     11:35  Xu lab‎ (diff | hist) . . (+239). . Peisheng Xu (talk | contribs) (Personnel)
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[Yar‎ (2×)]

     

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     06:53  Vectors‎ (diff | hist) . . (+422). . Wouter De Schamphelaire (talk | contribs) (Online vector databases)
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     17:20 (User creation log) . . User account Sandeep25789 (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎
     15:48  Yeo lab:Contact‎ (diff | hist) . . (-20). . Yoonyeo (talk | contribs) (Contact)

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Renhao Li Lab:Publications‎‎ (2 changes | history) . . (+255). . [Renhao Li‎ (2×)]

     

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     08:15  Peyton:Internal‎ (diff | hist) . . (+96). . Speyton (talk | contribs)
     05:16  Theobaldtwang:Data‎ (diff | hist) . . (+84). . Theobald, Tianwen Wang (talk | contribs)

14 August 2018

     16:18 (User creation log) . . User account Dtegs (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

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Chenlab:Recruiting‎‎ (2 changes | history) . . (+1,368). . [Kaifu Chen‎ (2×)]

     

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     08:49  Peyton:Internal‎ (diff | hist) . . (+60). . Carey Dougan (talk | contribs) (Protocols)
     08:48 (Upload log) . . Carey Dougan (talk | contribs) uploaded File:3D Printing Protocol.pdf

13 August 2018

N    19:50  BuildACell\CellFree\DataRepository‎ (diff | hist) . . (+381). . Wpoole (talk | contribs) (Created page with "{| Experiment Title | Contributor (with email) | Experiment Date | Extract Type and Organism (eg E. Coli S30, PURE) | Energy Solution Type or Identifier | Brief Comments on Ex...")
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