User:Liuzhec: Difference between revisions

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Revision as of 19:10, 25 April 2007


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<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="100"> </html>NEWS


<html> <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> </html> PLANNING


<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="0"> </html>WORKSHOP

<html> <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> </html> PROJECT



<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png"> </html> USEFUL LINKS

<html> <img src="http://openwetware.org/images/3/39/Icon_groups.png" alt="People"> </html>PEOPLE

Students


Advisors






Project Overview

  • Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
  • The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
  • As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
  • We expect that molecular containers could have several interesting scientific and clinical applications, such as
    • Drug and gene delivery
    • Bio-marker scavenging (early detection of biomarkers)
    • Directed evolution (compartmentalized selections)
    • Using multiplexing for combinatorial chemical synthesis
    • Capture and stabilization of multiprotein complexes
    • Protein folding (chaperones)
    • Cell sorting

==Working Team Members== edit

Recent Changes

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6 June 2024

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5 June 2024

     14:33  Production and Degradation Rate Papers‎‎ 10 changes history +3,266 [Nikkichun‎ (10×)]
     
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4 June 2024

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12:14 (cur | prev) +569 Nikkichun talk contribs (Created page with "After reviewing the data from this past year, it was found that production rates hold great significance in estimating GRNs. Trials with the initial toy network where P's were held constant gave much more accurate results than those where B's were held constant or no variables were held constant. Currently, these rates are based on the 2014 Neymotin et al. paper, but since this paper is now 7 years old, we wanted to investigate if there were more updated methods for calc...")

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