IGEM:Harvard/2006/DNA nanostructures
From OpenWetWare
Jump to navigationJump to search
Project Overview
- Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
- The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
- As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
- We expect that molecular containers could have several interesting scientific and clinical applications, such as
- Drug and gene delivery
- Bio-marker scavenging (early detection of biomarkers)
- Directed evolution (compartmentalized selections)
- Using multiplexing for combinatorial chemical synthesis
- Capture and stabilization of multiprotein complexes
- Protein folding (chaperones)
- Cell sorting
Working Team Members
- Tiffany Chan (talk, edits)
- Katherine Fifer (talk, edits)
- Valerie Lau (talk, edits)
- Matthew Meisel (talk, edits)
- Lewis Hahn (talk, edits)
- TA: Shawn Douglas (talk, edits)
Recent Changes
List of abbreviations:
- N
- This edit created a new page (also see list of new pages)
- m
- This is a minor edit
- b
- This edit was performed by a bot
- (±123)
- The page size changed by this number of bytes
12 December 2024
| 14:25 | CHIP:Talks diffhist 0 Gabor Balazsi talk contribs | ||||
|
|
m 11:02 | Griffin:Antigen Retrieval Technique 3 changes history +1,103 [Korey Griffin (3×)] | |||
| m |
|
11:02 (cur | prev) +109 Korey Griffin talk contribs (→Proteinase K Treatment) | |||
| m |
|
11:01 (cur | prev) −6 Korey Griffin talk contribs (→Proteinase K Treatment) | |||
| m |
|
11:00 (cur | prev) +1,000 Korey Griffin talk contribs | |||
| 09:23 | Hu:Publications diffhist −13 Hugangqing talk contribs | ||||
11 December 2024
| 14:04 | Xu lab:Lab Members diffhist +89 Peisheng Xu talk contribs (→Group Photo) | ||||
| N 12:17 | Schumer lab: Quick links document diffhist +134 Schumer talk contribs (Created page with "Master organizational link document: https://docs.google.com/document/d/1XeQ6orWeelxR7nkZUbUUIZd5VvZoj9d-WnqGsrJ4PjU/edit?usp=sharing") | ||||
|
|
12:16 | Schumer lab:Github and bioinformatics wiki 3 changes history +167 [Schumer; Tododge (2×)] | |||
|
|
12:16 (cur | prev) +61 Schumer talk contribs (→Where to find important files and resources?) | ||||
| m |
|
10:07 (cur | prev) +5 Tododge talk contribs | |||
|
|
10:04 (cur | prev) +101 Tododge talk contribs | ||||
| 12:15 | Schumer lab:General diffhist +208 Schumer talk contribs | ||||
|
|
N 10:42 | Schumer lab: Download data to Sherlock from UW (PacBio) 7 changes history +2,209 [Tododge (7×)] | |||
| m |
|
10:42 (cur | prev) −52 Tododge talk contribs (→Download data with Globus) | |||
| m |
|
10:36 (cur | prev) +6 Tododge talk contribs (→Rename files) | |||
|
|
10:36 (cur | prev) +15 Tododge talk contribs (→Delete unnecessary files) | ||||
| m |
|
10:35 (cur | prev) +176 Tododge talk contribs | |||
|
|
10:32 (cur | prev) +122 Tododge talk contribs (→Delete unnecessary files) | ||||
| m |
|
10:31 (cur | prev) +189 Tododge talk contribs (→Rename files) | |||
| N |
|
10:28 (cur | prev) +1,753 Tododge talk contribs (Created page with "==Download data with Globus== 1) info for JJ to fill in the important files are *hifi_reads.bc*.bam and *hifi_reads.bc*.bam.pbi # download all pacbio data from globus. the important files are *hifi_reads.bc*.bam and *hifi_reads.bc*.bam.pbi ==Delete unnecessary files== 1) delete fail_reads/ directory and unassigned.bam files <span style="font-family:Courier;"> cd /path/to/parent/directory/ <span style="font-family:Courier;"> rm -r fail_reads/ <span style="font-fa...") | |||
10 December 2024
| 05:26 | User:Andor J Kiss diffhist −121 Andor J Kiss talk contribs (→Links) | ||||
8 December 2024
| 17:19 | User:Yanbin Huang diffhist +269 Yanbin Huang talk contribs (→Peer-Reviewed Publications) | ||||
