Harvard:SysBio 204/2012
From OpenWetWare
Jump to navigationJump to search
Link to updated website for SysBio204 2014
Course overview
- A course focusing on the rational design, construction, and applications of nucleic acid and protein-based synthetic molecular and cellular machinery and systems. Students are mentored to produce substantial term projects.
- Intended for graduate students in Systems Biology, Biophysics, Engineering, Biology and related disciplines. No formal prerequisites. Projects are tailored to each student's strengths and interests.
- Website: http://synthetic-biology-class.net, http://sb204.net
- Poster
Midterm and Final
- There will be two midterms and one final project for this class
- Policy: strict submission deadline, we encourage you to submit your work the night before
- Midterm #1 due: Wed. Oct. 3, 12pm
- Midterm #2 due: Mon. Oct. 22, 12pm
- Final project due: Wed. Nov. 28, 2am
- Method of submission: email TA your slides and presentations
- Midterm and Final Projects
Logistics
- Instructors: George Church, William Shih, Pamela Silver, Peng Yin
- Meeting time: 2 pm – 3:30 pm, Mon/Wed, Fall 2012
- Location: Room 521, Wyss Institute, 3 Blackfan circle, Boston, 02115
- First class on Wednesday Sep 5th.
- Location: CLSB521
- No exams
- Prerequisites: none
- Grading
- 20% Participation
- 40% Midterm projects
- 40% Final project
- Harvard Course Site
Background Info and previous class projects
- BPH242r 2008-2009 http://openwetware.org/wiki/Biophysics_242r/2009 (Synthetic Biology)
- BPH242r 2010-2011 http://openwetware.org/wiki/Harvard:Biophysics_242r/2011 (Biologically Inspired Molecular Engineering)
- SB204 2011-2012 http://openwetware.org/wiki/Harvard:SysBio_204/2011 (Biologically Inspired Molecular Engineering)
Example topics for final design project
- miRNA pattern recognition in eukaryotic cells
- Directed evolution of chemical sensors
- Nano-breadboards for probing electron transport in proteins
- Altered genetic codes and amino acid alphabets
- Modification of proteins for function in harsh environments
- Automatable assembly of large synthetic genes and circuits
- Synthetic biology of stem cells and epigenetic reprogramming pathways
- Structural re-engineering of adenoviruses
- Artificial chemotactic swimmers
- Nonequilibrium networks of nano-machines mimicking dynamic instability in the cytoskeleton
- Recombinase-based multi-state memory in bacteria
- Exosome manufacturing
- Self-assembled solar energy harvester based on bio-inorganic nano-antennae for uv-vis
- Systematic debugging of DNA labeling chemistries by atomic-resolution TEM imaging of DNA origami
- Transcriptional activation and repression through rational molecular design
- Tissue engineering scaffold nano-materials
- Programmable multistep chemical synthesis by templating on catalytic nanostructures
- Ultra-sensitive signal processing for synthetic biology
- Antibody 2.0
- Synthetic nanostructure - virus conjugates
- Replication of information in synthetic crystals
- Cheap large-scale production of protein or DNA-based materials
- Etc. Etc. Etc.
Recent changes
List of abbreviations:
- N
- This edit created a new page (also see list of new pages)
- m
- This is a minor edit
- b
- This edit was performed by a bot
- (±123)
- The page size changed by this number of bytes
19 August 2022
| 11:35 | User creation log User account QLab J2022 talk contribs was created by Yar talk contribs and password was sent by email | ||||
18 August 2022
| 19:41 | Upload log Peisheng Xu talk contribs uploaded File:Xu Lab Xiaolong.png | ||||
| 19:26 | Xu lab diffhist −2 Peisheng Xu talk contribs | ||||
| 19:25 | Xu lab:Lab Members diffhist +123 Peisheng Xu talk contribs →Graduate Student | ||||
| m 01:26 | E. coli genotypes diffhist +56 Shyam Bhakta talk contribs strain ER2925 info | ||||
| m 00:35 | Forster Lab diffhist +43 Anthony C. Forster talk contribs minor edit to publication list | ||||
17 August 2022
|
|
16:16 | Schumer lab: Commonly used programs 4 changes history +228 [Gpreising (4×)] | |||
|
|
16:16 (cur | prev) +44 Gpreising talk contribs →Aligning long sequences | ||||
|
|
15:52 (cur | prev) +1 Gpreising talk contribs →Aligning long sequences | ||||
|
|
15:52 (cur | prev) −2 Gpreising talk contribs →Aligning long sequences | ||||
|
|
15:51 (cur | prev) +185 Gpreising talk contribs →Aligning fasta sequences | ||||
| 15:43 | Holcombe:PositionAndMotion diffhist +394 Alex O. Holcombe talk contribs | ||||
| 11:51 | CAMRI:Training diffhist −58 Lacey Berry talk contribs →Information on Training Sessions | ||||
16 August 2022
| 13:00 | Chenlab:Publications diffhist +4 Kaifu Chen talk contribs | ||||
|
|
11:45 | Chenlab:Lab Members 4 changes history +233 [Kaifu Chen (4×)] | |||
|
|
11:45 (cur | prev) −5 Kaifu Chen talk contribs | ||||
|
|
11:44 (cur | prev) +1 Kaifu Chen talk contribs | ||||
|
|
11:44 (cur | prev) −6 Kaifu Chen talk contribs | ||||
|
|
11:43 (cur | prev) +243 Kaifu Chen talk contribs | ||||
| 11:11 | Schumer lab: Commonly used programs diffhist −6 Gpreising talk contribs →Aligning long sequences | ||||
|
|
10:29 | (Upload log) [Yuezhang (2×)] | |||
|
|
10:29 Yuezhang talk contribs uploaded File:NoisySpeechProjectSetup SOP Beauchamplab.pdf | ||||
|
|
10:29 Yuezhang talk contribs uploaded File:NoisySpeechMATLAB SOP Beauchamplab.pdf | ||||
| 10:29 | Beauchamp:iEEG EMU MATLAB SOP diffhist +97 Yuezhang talk contribs →SOP for running MATLAB in EMU(Jan2022) | ||||
| 10:28 | Beauchamp:iEEG EMU SOP diffhist +102 Yuezhang talk contribs →Overview | ||||
| 10:02 | RAVE:Install diffhist +609 Zhengjia talk contribs →Updating RAVE | ||||
15 August 2022
| 20:47 | Renhao Li Lab:Publications diffhist +66 Renhao Li talk contribs →2022 | ||||
| 18:15 | Holcombe:PositionAndMotion diffhist +1 Alex O. Holcombe talk contribs | ||||
|
|
14:25 | Chenlab:Publications 2 changes history +269 [Kaifu Chen (2×)] | |||
|
|
14:25 (cur | prev) +14 Kaifu Chen talk contribs | ||||
|
|
14:24 (cur | prev) +255 Kaifu Chen talk contribs | ||||
| 14:10 | CAMRI:Training diffhist +2 Lacey Berry talk contribs →CAMRI USER TRAINING INFORMATION | ||||
14 August 2022
| 14:15 | Eccles: Lab meeting schedule diffhist +51 MikeEccles talk contribs →Lab meeting schedule | ||||
|
|
01:29 | Sangdunchoi:Papers 5 changes history +59 [Rameez99 (5×)] | |||
|
|
01:29 (cur | prev) +160 Rameez99 talk contribs →2022 | ||||
|
|
01:27 (cur | prev) +44 Rameez99 talk contribs →2022 | ||||
|
|
01:27 (cur | prev) +190 Rameez99 talk contribs →2022 | ||||
|
|
01:24 (cur | prev) +34 Rameez99 talk contribs →2022 | ||||
|
|
01:20 (cur | prev) −369 Rameez99 talk contribs →2021 | ||||