OpenSourceMalaria:Compound Series

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A summary of progress in the OSM project may be found in the Story so Far. The pages below include the technical detail of the individual series examined and are written for scientific contributors.

Series 1: GSK Arylpyrroles (Paper has been released: http://pubs.acs.org/doi/full/10.1021/acscentsci.6b00086)

Series 2: GSK Triazoloureas (parked)

Series 3: GSK Thienopyrimidines (work is resuming)

Series 4: Triazolopyrazines (TP series) (current priority)

Series 4: Mechanism of Action

Synthetic Branches

Obtaining Compounds for OSM

Repurposing

Other Possible GSK Series

Other Possible Series and Targets

Epigenetic Regulation of Lifecycle