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Juan Manuel Pedraza

Systems Biology Department
Harvard Medical School
200 Longwood Ave
Boston, MA 02115

firstname_lastname AT

Research Interests

Stochasticity in signalling and gene expression
Phenotypic variability as survival strategy
Control in synthetic genetic circuits
Evolution of social behaviour (for now, in microorganisms)
Anomalous diffusion, symbolic dynamics and hamiltonian chaos


Harvard University , Boston, MA

Postdoctoral Research Fellow in Systems Biology, 2006-

Massachusetts Institute of Technology, Cambridge, MA

Ph.D. in Physics, Feb. 2006.

University of the Andes, Bogota, Colombia

B.Sc. in Mathematics (4 year program), 2000.

B.Sc. in Physics (5 year program), 1999.


  1. Effects of molecular memory and bursting on fluctuations in gene expression

                   J.M. Pedraza and J. Paulsson
    Science, 319, 339 (2008).
  1. Stochastic gene expression out-of-steady-state in the cyanobacterial circadian clock

                   J.R. Chabot, J.M. Pedraza, P. Luitel and A. van Oudenaarden
    Nature, 450, 1249 (2007).
  1. Predicting stochastic gene expression dynamics in single cells

       J.T. Mettetal, D. Muzzey, J.M. Pedraza, E.M. Ozbudak and A. van Oudenaarden
    PNAS USA, 103, 7304, (2006).
  1. Noise in gene regulatory networks

                  J. M. Pedraza and A. van Oudenaarden
    In Complex Systems Science in BioMedicine (Springer, New York, 2006).
  1. Noise propagation in gene networks

                  J. M. Pedraza and A. van Oudenaarden
    Science, 307,1965 (2005).
  1. Non regular languages in the kicked rotor

                  P.-M. Binder and J. M. Pedraza 
    Physical Review E, 62, R5883 (2000).
  1. An invertibility paradox

                  P.-M. Binder, J. M. Pedraza, and S. Garzon. 
    American Journal of Physics, 67, 1091 (1999)