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Aminoglycosides: Difference between revisions
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==Comparison== | ==Comparison== | ||
Kanamycin and gentamycin affect bateria at lower concentrations than eukaryotes. Therefore, they can be used to target bacteria in animals during disease. G418 is more spefific for eukaryotic 80S ribosomal subunit and will harm cells without neo-resistence gene. | Kanamycin and gentamycin affect bateria at lower concentrations than eukaryotes. Therefore, they can be used to target bacteria in animals during disease. G418 is more spefific for eukaryotic 80S ribosomal subunit and will harm cells without neo-resistence gene. G418 and kanamycin both work on bacteria but the latter is cheaper. | ||
==Links== | ==Links== | ||
* Wikipedia entry [http://en.wikipedia.org/wiki/Aminoglycoside] | * Wikipedia entry [http://en.wikipedia.org/wiki/Aminoglycoside] | ||
* Bioforum thread on aminoglycosides [http://www.protocol-online.org/forums/index.php?showtopic=16774] | * Bioforum thread on aminoglycosides [http://www.protocol-online.org/forums/index.php?showtopic=16774] | ||
