Aminoglycosides: Difference between revisions
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'''Aminoglycosides''' are antibiotics effective against some bacteria. Note that aminoglycosides derived from ''Streptomyces'' species are named with the suffix | '''Aminoglycosides''' are antibiotics effective against some bacteria. Note that aminoglycosides derived from ''Streptomyces'' species are named with the suffix ''-mycin'', while those derived from ''micromonospora'' are named with the suffix ''-micin''. (These antibiotics are misspelled frequently). | ||
==Members common in the lab== | ==Members common in the lab== | ||
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==Comparison== | ==Comparison== | ||
Kanamycin and gentamycin affect bateria at lower concentrations than eukaryotes. Therefore, they can be used to target bacteria in animals during disease. G418 is more spefific for eukaryotic 80S ribosomal subunit and will harm cells without neo-resistence gene. | |||
==Links== | ==Links== | ||
* Wikipedia entry [http://en.wikipedia.org/wiki/Aminoglycoside] | * Wikipedia entry [http://en.wikipedia.org/wiki/Aminoglycoside] | ||
* Bioforum thread on aminoglycosides [http://www.protocol-online.org/forums/index.php?showtopic=16774] | * Bioforum thread on aminoglycosides [http://www.protocol-online.org/forums/index.php?showtopic=16774] | ||
Revision as of 13:55, 4 August 2006
Aminoglycosides are antibiotics effective against some bacteria. Note that aminoglycosides derived from Streptomyces species are named with the suffix -mycin, while those derived from micromonospora are named with the suffix -micin. (These antibiotics are misspelled frequently).
Members common in the lab
- G418 = geneticin
Comparison
Kanamycin and gentamycin affect bateria at lower concentrations than eukaryotes. Therefore, they can be used to target bacteria in animals during disease. G418 is more spefific for eukaryotic 80S ribosomal subunit and will harm cells without neo-resistence gene.
