# Isai Lopez Individual Journal 4

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# LAB 3 WRITE-UP

## Descriptive Stats and Graph

1) Oral Thermometer

Gold Standard Measurements for Temperature:
Mean: 96.637709
Standard Deviation: 1.920911

Spree Measurements for Temperature:
Mean: 95.54489
Standard Deviation: 0.877778

2) Pulse Ox

Gold Standard Measurements for Heart Rate:
Mean: 98.08977
Standard Deviation: 23.03054

Spree Measurements for Heart Rate
Mean: 98.9538
Standard Deviation:24.87754

## Inferential Stats

1) Oral Thermometer and Spree Band

Pearsons-R: 0.1509

Paired T-Test: 2.791*10^-20

2) Pulse Ox and Spree Band

Pearsons-R: 0.690806

T-Test: 0.427116

## Design Flaws and Recommendations

Based on the statistical evidence on temperature of the gold standard in comparison to the spree, the paired t-test concludes that the p-value of the experiment for temperature is about zero. Thus, this is less than alpha at 0.05 so we reject the null hypothesis that there is a relationship or equivalence between the data for temperatures for the spree and the Gold Standard. In addition, our correlation coefficient of 0.151 indicates that there is a weak, positive correlation between the temperatures recorded for the spree and the temperatures recorded for the Gold Standard. In conclusion, we can infer that overall the spree does not efficiently provide equivalent measurements of temperature to the Gold Standard.

Based on the statistical evidence on heart rate of the gold standard in comparison to the spree, the paired t-test concludes that the p-value of the experiment for heart rate is about 0.427. Since the p-value is greater than alpha at 0.05, we fail to reject the null hypothesis and cannot conclude that there is not a relationship or equivalence between the spree and the Gold Standard in heart rate. In addition, the

## Experimental Design of Own Device

Our group's scientific question is “Does the method in which galantamine is inserted into the body affect how much of the actual drug goes into the bloodstream?” In order to test if our device is valid and safe, our team has decided to put our device through clinical trials. In our experiment, we will have the sample size of 120 patients with Alzheimer's disease. The reason for why we chose 120 patients is because this is our first clinical trial and our team wants to see if it works on a smaller scale, compared to a much bigger one. In our experiment, our independent variable is the form in which the patients receive galantamine, a drug for those suffering from dementia. Galantamine is a drug used by patients with dementia. This drug was created to improve memory, awareness, and the ability to perform daily functions. In this experiment, we will divide the group of 120 people into three groups. Thus, each group will have 40 people. In one group the patients will receive the pill version of galantamine. In the second group, they will have out decide implanted in their mouths. In the drug reservoir will have the same amount of galantamine as the pill version. In the third group, the patients will not use galantamine at all. Our dependent variable is how much of galantamine goes into the patient's blood system. The control in this experiment is the amount of drugs each person receives whether it's in pill or liquid form stored in drug reservoir in the implant. The suggested amount of galantamine a person who uses the capsule version of the drug is 16 milligrams. Therefore, there would be ____ milliliters in the reservoir. The way in this experiment will work is that both the group one and two will take the drug at the same time. The caregiver will make sure that their patient receives their capsule at 8 in the morning and again at 4 pm. On the other hands, the implants will be set off too insert the drug at those exact times also. Then, at the end of the day, our group will go around taking blood samples of each patient while recording the data. This experiment will be a week long. Our hypothesis is “if patients use our product than, more galantamine will be inserted into the body because our product injects the drug directly into a vein located under the tooth”. After conducting this experiment we will review our results and see if our hypothesis is correct.