Chan:Daniël P. Melters

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Chan Lab

Department of Plant Biology at UC Davis

Daniël is a second year graduate student from the Cell and Developmental Biology Graduate Group and he is a shared student with Ian Korf. Daniël is also a member of the Designated Emphasis in Biotechnology, and is currently on his first year with the DEB's NIH training grant in Biomolecular Technology.

Daniël joined the lab in Spring of 2009, and his research project is focused on the evolution of the centromere repeat sequences in eurkaryotes using bioinformatics.

Daniël received his BSc and MSc from Leiden University in the Netherlands. For his MSc he worked in Dr. Lipsky's lab at the NIH, studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in Prof. Dr. de Kloet's lab at the LACDR / Leiden University identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined Dr. Pearce's lab at UCSF, working on understanding the signaling cascade regulation sodium reabsorption in kidney epithelium cells upon aldosterone treatment. His work has led to two publications:
- Soundararajan R, Melters DP, Shih IC, Wang J, Pearce D. Epithelial sodium channel regulated by differential composition of a signaling complex. Proc. Natl. Acad. Sci. U.S.A. 2009 106(19):7804-7809. link
- Soundararajan R, Wang J, Melters DP, Pearce D. Differential activities of glucocorticoid-induced leucine zipper protein isoforms. J. Biol. Chem. 2007 Dec 14;282(50):36303-13. link

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