BYU iGEM/Archive
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Parts Database
[iGEM Biological Parts Database]
Articles
OxyR_Peroxide
Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol—disulfide status. [1]
Redox sensing by prokaryotic transcription factors. [2]
OxyR_Binding
Computation-Directed Identification of OxyR DNA Binding Sites in Escherichia coli. [3]
OxyR_End
Sequence Data
OxyR Binding domain on the mnth gene
Site 1: TTTTCGTAGTCATAATCCTGGTCTATCAGAGAAATCA Source: [4]
Site 2: CTATCAGAGAAATCACCACAATCCATTTAAATGAATT Source: [5]
SoxR Binding domain on the SoxS gene
Site 1: AATCGCTTTACCTCAAGTTAACTTGAGGAATTATACTCC [6]
E. coli Colon cancer detector
Thermosensors
That paper that Dr. Griffitts suggested
PDF with ΔTRS mutation sequences
Multiple Cloning Site Map
Useful ROS Transcription factor articles
Ecocyc.org (anything you want to know about E. coli
Redox-operated genetic switches: the SoxR and OxyR transcription factors (Review)
Techniques to isolate O2-sensitive proteins: [4Fe-4S-FNR as an example.]
A genetically encoded sensor for H2O2 with expanded dynamic range (OxyR with YFP)
Rapid in vivo screening system for anti-oxidant activity using bacterial redox sensor strains.
Cellular Defenses against Superoxide and Hydrogen Peroxide
AND Gate Articles
Logical "And" switch part from iGEM registry
Other Colon Cancer Articles
Colon Cancer biomarker (Lgr5 protein)
Redox signaling and gene control in the Escherichia coli soxRS oxidative stress regulon - A review
The Universal Character of the Tumor-Associated Antigen Survivin
Biomarkers for Early Detection of Colon Cancer
OxyR and Soxr Transcription Factors
Biomarkers
Parts that activate translation at 37°C -- for more parts, change the final 2 in URL to 3 or 9
Bio Thermometer 1 (youTube video)
ROS is decreased in cancerous cells
Toolbox
Synthetic Biology and Engineering Rules
Directed Evolution of a Genetic Circuit
Inversion Recombinase Mechanisms
Schools for Synthetic Biology [7]
Potential Mechanisms
