BME100 s2014:W Group5 L2
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LAB 2 WRITE-UP
The purpose of this experiment is to find out the minimum LPS dosage required in order to have a significant effect on blood inflammotin concentration. We had a look at two broad groups in our study – humans and rats. These groups were then separated into subgroups according to treatment. Analysis of results is as follows:
For our human trials, we had five different treatment groups receiving 0mg, 5mg, 10mg or 15mg of LPS. P-score analysis of every possible combination of these groups showed a statistically significant difference (p < 0.008333333) for each and every one of these pairings as well as the ANOVA. Based on these numbers we can predict that treatment will have an effect on blood inflammotin levels and that the higher the dosage (up to 15mg), the greater the response.
Rat trials were slightly less complicated as we only compared treatments of 0mg and 10mg of LPS. The p-value between these two groups is 0.867 – this is not statistically significant and so the treatment is deemed to have no effect.