BME100 s2014:T Group6 L2

BME 100 Fall 2013	Home People Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3 Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6 Course Logistics For Instructors Photos Wiki Editing Help
OUR TEAM Name: Doan-Nhi T. Tran Name: Mark A. Keppler Name: Rayan S. Altayyar Name: Nicole D. Fisk Name: Brittani M. Ogden LAB 2 WRITE-UP Descriptive Statistics The Effect of Lipopolysaccharide in Human Subjects Inflammotin Concentration by Dosage for 0mg Trial (pg/ml) Mean: 3.834 Standard Deviation: 1.523 Standard Error: 0.482 Inflammotin Concentration by Dosage for 5mg Trial (pg/ml) Mean: 8.932 Standard Deviation: 1.594 Standard Error: 0.504 Inflammotin Concentration by Dosage for 10mg Trial (pg/ml) Mean: 61.622 Standard Deviation: 30.111 Standard Error: 0.9.522 Inflammotin Concentration by Dosage for 15mg Trial (pg/ml) Mean: 657.941 Standard Deviation: 212.943 Standard Error: 67.338 The Effect of Lipopolysaccharide in Rat Subjects Inflammotin Concentration by Dosage for 0mg (pg/ml) Mean: 10.512 Standard Deviation: 2.226 Standard Error: 0.995 Inflammotin Concentration by Dosage for 10mg (pg/ml) Mean: 11.112 Standard Deviation: 7.403 Standard Error: 3.311 Results [Graphs unavailable] Analysis ANOVA Test on the Effect of Lipopolysaccharide in Human Subjects In order to properly demonstrate the significance of our statistical correlations in human trials we conducted the ANOVA test since we had 4 separate groups with 10 subjects per group. Each group received a different dose of lipopolysaccharide incremented in 5 mg portions. ANOVA returned a p value of 1.401E-16 signifying a confidence several orders of magnitude greater than the required 0.05 p value. We followed up our analysis by including comparative T-Tests in order to demonstrate significance between each possible combination of paired groups. All returned T-Test values were found to be several orders of magnitude greater than the required confidence interval. T-Test on the Effect of Lipopolysaccharide in Rat Subjects In order to properly demonstrate the significance of correlation within our two rat trials we conducted a T-Test which returned a p value of 0.867. This value does not correlate within our required interval of 0.05 which demonstrates that the lipopolysaccharide did not significantly induce Inflammotin accumulation. Summary/Discussion Lipopolysaccharide has been found to be significant in human trials with greater than 99.99% confidence at all tested concentrations. Significance has also been demonstrated between test groups using T-Test analysis for all possible pair combinations. Rat trials however only demonstrate a confidence of 13.26% which does not meet the minimum 95% requirement.