BME100 f2016:Group4 W8AM L1

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BME 100 Fall 2016 Home
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Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3
Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6
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OUR TEAM

Name: Nathalie Nunez
Name: Danielle Morelan
Name: Manyta Parmar
Name: Mark Mcpherson
Name: Shannon Medovich
Name: Your name

LAB 1 WRITE-UP

Health Care Issue

Lyme Disease: In the U.S., Lyme Disease is the most common vector-borne illness. It is spread to humans by ticks, and the illness involves the body's response to the infection caused by Borrelia burgdorferi.


N/A. "About Lyme Disease." LymeDisease.org. LymeDisease.org, n.d. Web. 1 Sept. 2016. <https://www.lymedisease.org/lyme-basics/lyme-disease/about-lyme/>.

Competitors

Western Blotting
Advantages
-Highly specific interaction between an antibody and an antigen
-Detects proteins based on size and does not need to bind specifically to any 1 epitopes
-Uses fluorescence

Disadvantages
-56% of tests are inaccurate (unexpected bands, no bands, misplaced bands)
-Takes a long time
-More difficult test
-Costly


“ELISA” (enzyme-linked immunosorbent assay)
Advantages
-High Sensitivity
-Strong specificity
-Cheap ($80-300)
-No radioactivity

Disadvantages
-Antibodies are more difficult to find
-Enzyme/substrate reaction is short term so micro-wells must be read quickly


N/A. "Lyme Disease." Cdc.gov. Center for Disease Control and Prevention, n.d. Web. 1 Aug. 2016. <https://www.cdc.gov/lyme/>. N/A. "A Guide: The Diagnostic Dilemma of Lyme Disease."LymeResearchAlliance.org. Lyme Research Alliance, n.d. Web. 01 Sept. 2016. <http://www.lymeresearchalliance.org/test-diagnostic.html>.

Customer Validation

Patient
Someone with Lyme's Disease

Payer
Health Insurance

Physician
Primary care physicians-Rheumatologist (Specialists)

Provider
Hospitals

Purchaser
Drug Research Companies

IP Position


Application Number/ Assignee_|________Title________|________Summary___________|___Filing date/ Status____


US10323204_______________|_Data processing and_|_It includes accessing_________|2002-12-18 -Active
GE Medical Systems_________|feedback method and_|_image data for______________|_expires 2025-01-31
Global Technology Co LLC____|_system____________|_evaluation._________________|


US09300971_______________| Peptides and assays__| Quick diagnosis using________| 1999-04-28 -Active
Administrators of the Tulane___| for the diagnosis of____| proteins with specific________|expires 2019-04-28
Educational Fund___________| lyme disease_________| peptide and nucleic acid______|
______________________________________________| to sequence the proteins_____|


Fundability Worksheet Scores

Competitors
2-There are competitors, however, improvements are much needed because the tests to detect lyme disease are often inaccurate, expensive, or very time-consuming.

Customer Validation
3-While there have not been any conversations with customers, it can be assumed that those who are in areas common with lyme disease would be very interested in this product so that they can avoid getting the illness.

IP Position
3-There are patents in the detection of lyme disease.