BME100 f2016:Group1 W8AM L1
|BME 100 Fall 2016|| Home |
Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3
Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6
Course Logistics For Instructors
Wiki Editing Help
LAB 1 WRITE-UP
Health Care Issue
Diabetes is a disease that affects millions of people worldwide. "Insulin Dependent Diabetes Mellitus (IDDM) is a type of organ specific autoimmune disorder characterized by the destruction of pancreatic beta cells by cytotoxic T cells. About 1,000 insulin secreting beta cells are located in a spherical cluster called an islet of Langerhans. These islets make up 1-2% of pancreatic mass, are scattered throughout the pancreas, and contain other secreting cells. The autoimmune attack on the beta-cells, compromises the production of insulin and thereby the functions associated with insulin.The attack on beta-cells is initiated by activated cytotoxic T-lymphocytes (CTLs) that target specific islets for lysis (destruction). The CTL activity triggers the release of cytokines (immune hormonal messengers) which in turn stimulate the proliferation of activated macrophages and autoantibodies that are attracted to the site of inflammation (immune activation). The autoantibodies, together with complement-mediated lysis as well as macrophage and CTL activity, are responsible for the overall destruction of pancreatic tissue" ("The Pathology of Diabetes," n.d.).
Blood Glucose Monitoring Devices
1) Number/Assignee: Application number: EP20110156507
Publication number: EP2494920 A1
Title: Medical device capable of measuring a blood glucose level containing a data projector.
Summary: According to the invention, the display device (3) comprises a projector unit (3.2) with a light source and an array of optical elements (3.2.11). The projector unit (3.2) is capable of optically projecting and displaying an image (I) on a suitable surface (6) like, for example, a wall or a ceiling(GmbH,2011) Filing date/Status:March 2, 2011.
2) Number/ Assignee: Application number: US 14/494,517
Publication number: US20150141871 A1 Original assignee: Kaveh Khast
Title: Pain minimizing injection system
Summary: The invention incorporates a lancet and a glucose test strip into a disposable cartridge. The user inserts the cartridge into the port of the device to turn it on. The base vibrates to quench or reduce pain from a lancet puncture. The test strip is exposed to the blood sample at the site of the lancet puncture which is analyzed by the device(Khast & Julian,2014). Filing date/ Status: September 23, 2014
3) Number/ Assignee: Application number: US 12/588,733
Publication number: US8385998 B2 Original assignee: Jin Zhang , William Gerald Hodge
Title: Contact lens integrated with a biosensor for the detection of glucose and other components in tears.
Summary:These contact lenses can be worn by diabetics who can colorimetrically see changes in their contact lens color or other fluorescence-based properties, giving an indication of tear and blood glucose levels(Zhang and Hodge, 2009). Filing date/ Status: October 26, 2009
4) Number/ Assignee: Application number: US 12/153,647
Publication number: US9244035 B2 Assignee: Northeastern University
Title: Saliva Glucose monitoring system
Summary:Fabrication of the sensor involves depositing single-walled carbon nanotubes onto the surface of a working electrode in a 3 electrode electrochemical detector and functionalizing the nanotubes by depositing layers of polymers, metallic nanoparticles, and glucose oxidase enzyme onto the nanotubes. The sensor can be used as a disposable, single-use device or as part of an analytical system, such as a microfluidics system, for the analysis of multiple analytes. The sensor enables the diagnosis and monitoring of diabetes to be performed without pain or the need for finger pricks in a home or clinical setting(Zhang, Wang, and Northeastern, 2014) Filing date/ Status: January 13, 2014
1)Bibliographic data (2012) Available at: https://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=2494920A1&KC=A1&FT=D (Accessed: 7 September 2016).
2)Patent images (2015) Available at: http://pdfaiw.uspto.gov/.aiw?docid=20150141871&SectionNum=2&IDKey=CEF68CCD1D12&HomeUrl=http://appft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1%2526Sect2=HITOFF%2526d=PG01%2526p=1%2526u=/netahtml/PTO/srchnum.html%2526r=1%2526f=G%2526l=50%2526s1=20150141871.PGNR.%2526OS=%2526RS= (Accessed: 7 September 2016).
3)Bibliographic data (2012) Available at: https://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=2494920A1&KC=A1&FT=D (Accessed: 7 September 2016).
4)Zhang, W., Wang, M.L. and Northeastern (2014) Patent US9244035 - saliva glucose monitoring system. Available at: https://www.google.com/patents/US9244035?dq=US+14/153,647&hl=en&sa=X&ved=0ahUKEwjA7ZiUz_zOAhUIz2MKHTAQBwsQ6AEIHjAA (Accessed: 7 September 2016).
The desired place would be at local hospitals or clinics to be supplied there.
Some of the patented products are very similar in concept, but are subject to change.
Fundability Worksheet Scores