BME100 f2014:Group20 L6
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Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3
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LAB 6 WRITE-UP
Overview of the Original Diagnosis System
When testing patients for the disease-associated SNP, BME 100 split the labor up throughout the groups. With 34 teams of 6 students, 68 patients were able to be tested. This is a good division of labor in that while each group only needed to test two patients, the entire group was able to test 68. This helps on the larger scale. Many things were done to help prevent error. By receiving three replicate DNA samples from the two patients, it ensured multiple trials and a higher chance of success. After all the tests were conducted, the results yielded a total positive result of 30, and a total negative result of 24. Of these, eight were inconclusive, and for six of them there was no test.
What Bayes Statistics Imply about This Diagnostic Approach
The Bayes value for both one and two seem to be reliable in concluding that there is a good chance it is accurate in determining that a person has the disease SNP, because of the values being closer to 1.00. Some error could have come from a few sources. First off, the solution could have possibly been exposed for too long. Second, there is a possibility the ImageJ software was read incorrectly, or was maybe used incorrectly. Finally, there is a chance that the solutions may have been prepared incorrectly, causing wrong results.
Based on the Bayes value for calculations 3 and 4, it would seem that these values are not as accurate in determining if the person has the disease SNP, because of the values being further from 1.00.
Despite having the issue of the site going down for maintenance, the following is a summary of the TinkerCAD tool. This tool was used in place of a much more advanced CAD software such as Autodesk Inventor / Solidworks in order to introduce the freshman to digital design. It's use of pre-made shapes and easy dimensioning is helpful for those who are unfamiliar with drawing and extruding a shape.
Feature 2: Consumables Kit
The consumables will come in a plastic case with clasps to keep it closed. Everything will be organized and wrapped in plastic separately, to ensure it will remain organized.
Feature 3: Hardware - PCR Machine & Fluorimeter
The PCR thermocycler and the fluorimeter will be individually packaged within the box. Having them remain separated will leave the less prone to damage.