BME100 f2014:Group11 L1
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LAB 1 WRITE-UP
Independent and Dependent Variables
The inflammatory protein (Inflammotin) is the dependant variable because it is affected by changes in the independent variable: the inflammation inducing agent (lipopolysacchiride).
The groups will be selected in a way to minimize bias and balance both the known and unknown before treatment. Elderly participants who are between the ages of 65 and 70 years old will be the main subjects. These patients should have a moderate to severe inflammation condition. Aside from high inflammation we will be looking for mostly healthy participants (i.e. none critically ill) so other current or previous medical conditions would not skew the results from the trial. The gender ratio should be 3 female participants and 3 male participants in each trial group to ensure there is no gender bias and there will be consistency throughout all groups.
Sources of Error and Bias
Some potential sources of bias or error that could affect our results are: age, gender, environment, severity of inflammation, previous treatment history, and other medical conditions. A bias could be present if the patient has taken another prescription medication to treat inflammation and they may be comparing the results they receive from Inflammation to the results they had from that prior medication. An error could also be present if this drug reacts with any current medications the patient is on. Current and past medical conditions may also influence the results, but this adds to the randomness of the experiment and will give us more sound results on how the drug will affect people across the board. Environment could also cause an error because elevation causes different reactions with inflammation and the way the patients bodies may react.