User:Tushar N Patel

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Banta Lab

Protein and Metabolic Engineering

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Contact Info

  • Tushar Navin Patel
  • Columbia University
  • 500 W 120th St
  • 801 Mudd Building
  • New York, NY 10027

I am a graduate student in the Banta Lab at Columbia University in the Department of Chemical Engineering. Our lab works on protein and metabolic engineering for a variety of applications. My work is focused around heterogeneous biocatalysis and more specifically, the use of E. coli as a whole-cell biocatalyst.


  • 2014 (expected), PhD in ChemE, Columbia University, New York, NY
  • 2011, MS in ChemE, Columbia University, New York, NY
  • 2009, BS in ChemE, Northeastern University, Boston, MA


  1. Felsovalyi, F., Patel, T., Mangiagalli, P., Kumar, S. K. and Banta, S. (2012), Effect of thermal stability on protein adsorption to silica using homologous aldo-keto reductases. Protein Science, 21: 1113–1125. doi: 10.1002/pro.2099
  2. Patel, T.N., Park, A-H.A., and Banta, S. (2013), Periplasmic expression of carbonic anhydrase in Escherichia coli: A new biocatalyst for CO2 hydration. Biotechnology and Bioengineering. doi: 10.1002/bit.24863


  1. Patel, T., Swanson, E., Park, A-H., and Banta, S., "Development of a whole-cell biocatalyst for permanent carbon capture and storage: Immobilization of carbonic anhydrase in the periplasmic space of Escherichia coli", 243rd ACS National Meeting, San Diego, CA, March 25-29, 2012.
  2. Patel, T., Swanson, E., Park, A-H., and Banta, S., "Periplasmic Expression of Carbonic Anhydrase to Mediate Carbon Mineralization", 2012 AIChE Annual Meeting, Pittsburgh, PA, October 28-November 2, 2012.
  3. Patel, T., Swanson, E., Park, A-H., and Banta, S., "Whole-cell Biocatalysts for CO2 Hydration: Alternative Periplasmic Expression Systems and Cell Modifications to Improve the Overall Reaction Rate", 245th ACS National Meeting, New Orleans, LA, April 7-11, 2013.

Research interests

My research interests all relate to engineering and using biology for a variety of applications including catalysis, sensing, structural functions, biomaterials, and therapeutics.

  1. Protein Engineering
  2. Metabolic Engineering
  3. Synthetic Biology
  4. Heterogeneous Biocatalysis
  5. Biomaterials

Work Experience

  • Novartis Vaccines and Diagnostics, Cambridge, MA, June 2009-August 2009
    • Peptide-based nanoparticles as a novel drug delivery modality for protein-based drugs
  • Semprus BioSciences, Cambridge, MA, January 2008-July 2008
    • Anti-microbial coatings for biomedical devices
  • The Charles Stark Draper Laboratory, Cambridge, MA, January 2007-June 2007
    • Formulation of polymer-based Glucose-sensing nanooptodes
    • GC/MS analysis on human samples for biochemical markers