User:Sara Chuang

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Banta Lab

Protein and Metabolic Engineering

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Contact Info

Sara Chuang.
Sara Chuang

History

  • PhD Candidate at Princeton University in Chemical and Biological Engineering (2013-)

Gitai Lab & Stone Lab

  • Undergraduate researcher in the Banta Protein Engineering Lab at Columbia University (2010-2013)
  • Summer Intern at Bristol Myers Squibb (2012,2013)

Education

  • 2018 (expected), PhD, Chemical Engineering, Princeton University
  • 2013, BS, Chemical Engineering, Columbia University

Publications

  1. Campbell, E., Chuang, S., and Banta, S. (2013) “Modular exchange of substrate-binding loops alters both substrate and cofactor specificity in a member of the aldo-keto reductase superfamily” Protein Engineering, Design and Selection 26(3) 181-186.


Research interests

  1. Mechanical Cues for Bacteria Virulence
  2. Bacteria Coexistance
  3. Protein Engineering
  4. Pharmaceuticals

Research Projects

Current Project: Gitai/Stone Lab at Princeton

  • Mechanical Cues of Bacterial Virulence
  • Bacteria Coexistance

Past Projects:

  • Analyzing interactions of super charged proteins on surfaces (2012-2013)
  • Effects of protein stability on different surfaces (2011-2012)
  • Mutating an enzyme for use in bio fuel cells (2010-2011)

Work Experience

  • Drug Science Product Techology Summer Intern at Bristol Myers Squibb (Summer 2013)
    • Silicone Oil, Water and Protein Interactions
  • Chemical Development Summer Intern at Bristol Myers Squibb (Summer 2012)
    • Scale-up of a Packed Bed Reactor


Research Skills

  • RNASeq
  • Microarrays
  • Protein Expression in Ecoli
  • Protein His Trap Purification
  • FPLC (Fast Protein Liquid Chromatography)
  • Protein Structure analysis on Circular Dichroism
  • Gel electrophoresis
  • PCR, Ligations
  • Dynochem Modeling Software
  • Aspen Modeling
  • Micro-Flow Imaging