User:Christine Doan/Notebook/Synthetic Biology/2014/02/14

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Networking BioFlorida - Central Chapter[1] Co-Chair: Thad Seymour, PhD Lake Nona Phone: 407-816-6675 tseymour@lakenona.com Co-Chair: William Warren, PhD Sanofi Pasteur VaxDesign Campus Phone: (407) 243-5600 william.warren@sanofipasteur.com Because of the geographical challenge Florida presents, BioFlorida has implemented regional Chapters to serve its members throughout the state. There are no additional membership fees or Chapter-specific fees in the BioFlorida organization. Chapters were created to better facilitate communication with members at the local level; provide enhanced services to members; provide education and support to bioscience organizations throughout the state; and cover topics of interest to members in each respective region. Bioluminescence Aliivibrio fischeri Jesse: modifying the operon to act as a biosensor Ryan: find pathway to make luciferin Fluorescent proteins already exist that can be used as tags and sensors Standard protocol for identifying things or optimizing circuits Where to put it? Under what promoter? With what logic? What assembly method to use? Where are we sourcing it from? Brightness or sensor in logic circuit or output indicating expression of another gene? Bio-remediation Jesse: detection of small molecules found at marine spill sites? Emerick: ANALOG bio-sensing of polycyclic hydrocarbons or nitrates Synthetic analog computation in living cells [2] Experimentation with non-transgenic bio-remediation Systems biology approach using engineers and programmers http://www.youtube.com/watch/MT0qY3_n1kI Ryan: "if we search long enough we can find a bug that can degrade anything"