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2008 Transporter Group meetings: Lab research overview

Lab Research Projects/keywords/techniques
Bae LAT-1 targeted combination therapy of prostate cancer using intelligent nanovehicles

LAT-1, BCH, Brasilicardin A, HSP90, DDS and polymer nanovehicles

Graf ABC transporters in lipid xenobiotic metabolism and their influence of metabolic disease
Lee Function and regulation of OATP1B3 overexpressed in colon cancer
Leggas The role of efflux and uptake transporters on the pharmacokinetics of camptothecin analog DB67
Matthews endophyte toxicity-, aging-, and nutrient/substrate supply- regulation of transporters and enzymes expression by various tissues of ruminant phenotypes

MDBK cells, real-time RT-PCR, microarray, gel-based proteomics

McNamara Role of Transporters in Drug Exposure during Lactation

theoretical, cell culture and in vivo model, ABCG2, OATPs

Moscow OATP1B1, OATP1B3, microcystin, SLC22A16, THTR2, thiaminase I
Paumi Regulation of ABCC transporter function: The role of ABCC phosphorylation by protein kinases CKII and AMPK.

ABCC1, ABCC6, Ycf1p, Saccharomyces cerevisiae, Casein Kinase 2, AMPK, Protein interactors

Vore liver, heart, intestine, MRPs, Abcg5/g8, regulation of expression in lactation
Yokel Neurotoxic metal transport at the blood-brain barrier

aluminum, manganese, methods to assess brain influx and efflux, nanoscale materials