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Publications: 2006-2007

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Publications accessible in PubMed

  1. Misra J, Alevizos I, Hwang D, Stephanopoulos G, and Stephanopoulos G. Linking physiology and transcriptional profiles by quantitative predictive models. Biotechnol Bioeng. 2007 Sep 1;98(1):252-60. DOI:10.1002/bit.21540 | PubMed ID:17551988 | HubMed [127]
  2. Antoniewicz MR, Kraynie DF, Laffend LA, González-Lergier J, Kelleher JK, and Stephanopoulos G. Metabolic flux analysis in a nonstationary system: fed-batch fermentation of a high yielding strain of E. coli producing 1,3-propanediol. Metab Eng. 2007 May;9(3):277-92. DOI:10.1016/j.ymben.2007.01.003 | PubMed ID:17400499 | HubMed [126]
  3. Alper H and Stephanopoulos G. Global transcription machinery engineering: a new approach for improving cellular phenotype. Metab Eng. 2007 May;9(3):258-67. DOI:10.1016/j.ymben.2006.12.002 | PubMed ID:17292651 | HubMed [125]
  4. Ajikumar PK, Ng JK, Tang YC, Lee JY, Stephanopoulos G, and Too HP. Carboxyl-terminated dendrimer-coated bioactive interface for protein microarray: high-sensitivity detection of antigen in complex biological samples. Langmuir. 2007 May 8;23(10):5670-7. DOI:10.1021/la063717u | PubMed ID:17388617 | HubMed [124]
  5. Lütke-Eversloh T and Stephanopoulos G. L-tyrosine production by deregulated strains of Escherichia coli. Appl Microbiol Biotechnol. 2007 May;75(1):103-10. DOI:10.1007/s00253-006-0792-9 | PubMed ID:17221195 | HubMed [123]
  6. Taniguchi CM, Aleman JO, Ueki K, Luo J, Asano T, Kaneto H, Stephanopoulos G, Cantley LC, and Kahn CR. The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance. Mol Cell Biol. 2007 Apr;27(8):2830-40. DOI:10.1128/MCB.00079-07 | PubMed ID:17283057 | HubMed [122]
  7. Jin YS and Stephanopoulos G. Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metab Eng. 2007 Jul;9(4):337-47. DOI:10.1016/j.ymben.2007.03.003 | PubMed ID:17509919 | HubMed [121]
  8. Loose CR, Langer RS, and Stephanopoulos GN. Optimization of protein fusion partner length for maximizing in vitro translation of peptides. Biotechnol Prog. 2007 Mar-Apr;23(2):444-51. DOI:10.1021/bp060277o | PubMed ID:17269789 | HubMed [120]
  9. Tyo KE, Alper HS, and Stephanopoulos GN. Expanding the metabolic engineering toolbox: more options to engineer cells. Trends Biotechnol. 2007 Mar;25(3):132-7. DOI:10.1016/j.tibtech.2007.01.003 | PubMed ID:17254656 | HubMed [119]
  10. Nevoigt E, Fischer C, Mucha O, Matthäus F, Stahl U, and Stephanopoulos G. Engineering promoter regulation. Biotechnol Bioeng. 2007 Feb 15;96(3):550-8. DOI:10.1002/bit.21129 | PubMed ID:16964624 | HubMed [118]
  11. Stephanopoulos G. Challenges in engineering microbes for biofuels production. Science. 2007 Feb 9;315(5813):801-4. DOI:10.1126/science.1139612 | PubMed ID:17289987 | HubMed [117]
  12. Styczynski MP, Moxley JF, Tong LV, Walther JL, Jensen KL, and Stephanopoulos GN. Systematic identification of conserved metabolites in GC/MS data for metabolomics and biomarker discovery. Anal Chem. 2007 Feb 1;79(3):966-73. DOI:10.1021/ac0614846 | PubMed ID:17263323 | HubMed [116]
  13. Antoniewicz MR, Kelleher JK, and Stephanopoulos G. Elementary metabolite units (EMU): a novel framework for modeling isotopic distributions. Metab Eng. 2007 Jan;9(1):68-86. DOI:10.1016/j.ymben.2006.09.001 | PubMed ID:17088092 | HubMed [115]
  14. Alper H, Moxley J, Nevoigt E, Fink GR, and Stephanopoulos G. Engineering yeast transcription machinery for improved ethanol tolerance and production. Science. 2006 Dec 8;314(5805):1565-8. DOI:10.1126/science.1131969 | PubMed ID:17158319 | HubMed [114]
  15. Loose C, Jensen K, Rigoutsos I, and Stephanopoulos G. A linguistic model for the rational design of antimicrobial peptides. Nature. 2006 Oct 19;443(7113):867-9. DOI:10.1038/nature05233 | PubMed ID:17051220 | HubMed [113]
  16. Alper H, Miyaoku K, and Stephanopoulos G. Characterization of lycopene-overproducing E. coli strains in high cell density fermentations. Appl Microbiol Biotechnol. 2006 Oct;72(5):968-74. DOI:10.1007/s00253-006-0357-y | PubMed ID:16502313 | HubMed [112]
  17. Nevoigt E, Kohnke J, Fischer CR, Alper H, Stahl U, and Stephanopoulos G. Engineering of promoter replacement cassettes for fine-tuning of gene expression in Saccharomyces cerevisiae. Appl Environ Microbiol. 2006 Aug;72(8):5266-73. DOI:10.1128/AEM.00530-06 | PubMed ID:16885275 | HubMed [111]
  18. Antoniewicz MR, Kelleher JK, and Stephanopoulos G. Determination of confidence intervals of metabolic fluxes estimated from stable isotope measurements. Metab Eng. 2006 Jul;8(4):324-37. DOI:10.1016/j.ymben.2006.01.004 | PubMed ID:16631402 | HubMed [110]
  19. Styczynski MP, Fischer CR, and Stephanopoulos GN. The intelligent design of evolution. Mol Syst Biol. 2006;2:2006.0020. DOI:10.1038/msb4100065 | PubMed ID:16738565 | HubMed [109]
  20. Jensen K, Alper H, Fischer C, and Stephanopoulos G. Identifying functionally important mutations from phenotypically diverse sequence data. Appl Environ Microbiol. 2006 May;72(5):3696-701. DOI:10.1128/AEM.72.5.3696-3701.2006 | PubMed ID:16672519 | HubMed [108]
  21. Tyo KE, Zhou H, and Stephanopoulos GN. High-throughput screen for poly-3-hydroxybutyrate in Escherichia coli and Synechocystis sp. strain PCC6803. Appl Environ Microbiol. 2006 May;72(5):3412-7. DOI:10.1128/AEM.72.5.3412-3417.2006 | PubMed ID:16672485 | HubMed [107]
  22. Antoniewicz MR, Stephanopoulos G, and Kelleher JK. Evaluation of regression models in metabolic physiology: predicting fluxes from isotopic data without knowledge of the pathway. Metabolomics. 2006 Mar;2(1):41-52. DOI:10.1007/s11306-006-0018-2 | PubMed ID:17066125 | HubMed [106]
  23. Fischer CR, Alper H, Nevoigt E, Jensen KL, and Stephanopoulos G. Response to Hammer et al.: Tuning genetic control--importance of thorough promoter characterization versus generating promoter diversity. Trends Biotechnol. 2006 Feb;24(2):55-6. DOI:10.1016/j.tibtech.2005.12.001 | PubMed ID:16380177 | HubMed [105]
  24. Jensen KL, Styczynski MP, Rigoutsos I, and Stephanopoulos GN. A generic motif discovery algorithm for sequential data. Bioinformatics. 2006 Jan 1;22(1):21-8. DOI:10.1093/bioinformatics/bti745 | PubMed ID:16257985 | HubMed [104]
All Medline abstracts: PubMed | HubMed