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Degradable Sutures, by Cody Siroka: Difference between revisions
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Degradable Sutures, by Cody Siroka (view source)
Revision as of 20:53, 11 February 2015
, 11 February 2015→Current Use and Materials
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Sutures are important in promoting the healing process in damaged tissue and preventing further complications. Degradable sutures are useful in many wound closing applications, especially when the wound is minor. It is important that the best possible suture material is chosen based on the type of wound, bodily location, and other factors. For example, to minimize potential scarring where cosmetic implications are considerable, the smallest suture materials are generally chosen. The materials used to manufacture these sutures dictate the type of immune response, biocompatibility, and mechanical properties, consequently influencing wound treatment. | Sutures are important in promoting the healing process in damaged tissue and preventing further complications. Degradable sutures are useful in many wound closing applications, especially when the wound is minor. It is important that the best possible suture material is chosen based on the type of wound, bodily location, and other factors. For example, to minimize potential scarring where cosmetic implications are considerable, the smallest suture materials are generally chosen. The materials used to manufacture these sutures dictate the type of immune response, biocompatibility, and mechanical properties, consequently influencing wound treatment. | ||
=== Current Use and Materials === | === Current Use and Materials === | ||
[[Image:suturesizes.png|left|''[[Overview of suture sizes and intended uses.]]'']]Degradable suture materials can be either organic or synthetic. There are many types of materials which have been used over course of their development that are absorbed by the human body. Absorbable sutures tend to be reserved for use inside the body underneath the skin as they are prone to leave a more pronounce scar upon absorption. When later removal poses potential difficulty, their use may be exhausted. This list encompasses the most commonly used materials today. | [[Image:suturesizes.png|left|''[[Overview of suture sizes and intended uses.]]'']]Degradable suture materials can be either organic or synthetic. There are many types of materials which have been used over course of their development that are absorbed by the human body. Absorbable sutures tend to be reserved for use inside the body underneath the skin as they are prone to leave a more pronounce scar upon absorption. When later removal poses potential difficulty, their use may be exhausted. For synthetic materials, it is desirable that there is no toxicity associated with its usage, is metabolized fully, long-lasting shelf life, easy to manipulate, and is sterilizable. Many factors affect the performance of a synthetic material, which consequently yields variations among molecular weight, molecular weight distribution, hydrophobicity, and crystallinity. [8] This list encompasses the most commonly used materials today. | ||
<br>'''Catgut'''<br>[[Image:Wc.absorb.md_.chart_rev.jpg|right|upright=1|''[[Overview of commercial absorbable sutures, strength classification, and degradation time]]'']] | <br>'''Catgut'''<br>[[Image:Wc.absorb.md_.chart_rev.jpg|right|upright=1|''[[Overview of commercial absorbable sutures, strength classification, and degradation time]]'']] | ||
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Synthetic heteropolymer of 90% glycolide, and 10% lactide. This type of material is more pliable than other synthetics. The production of polyglycan utilizes a catalyst, where the materials are melted and extruded into fibers and treated. The degradation of polyglycan is by hydrolysis. Coatings may be used to improve handling of the material. The retention of tensile strength is comparable to that of PGA, where polyglycan may be a bit greater (4). <br> | Synthetic heteropolymer of 90% glycolide, and 10% lactide. This type of material is more pliable than other synthetics. The production of polyglycan utilizes a catalyst, where the materials are melted and extruded into fibers and treated. The degradation of polyglycan is by hydrolysis. Coatings may be used to improve handling of the material. The retention of tensile strength is comparable to that of PGA, where polyglycan may be a bit greater (4). <br> | ||
'''Polydioxanone (PDS)''' | '''Polydioxanone (PDS)''' | ||
<br>Synthetic homopolymer, prepared through the polymerization of the monomer paradioxanone, which is melt excluded into a monofilament. The synthetic material is again broken down by hydrolysis. Two weeks after implementation, it retains approbimately 70% of its initial tensile strength (4), and maintains its strength quite well compared to other materials, which implies that this material is preferred for wounds which are closed with tension. | <br>Synthetic homopolymer, prepared through the polymerization of the monomer paradioxanone, which is melt excluded into a monofilament. The synthetic material is again broken down by hydrolysis. Two weeks after implementation, it retains approbimately 70% of its initial tensile strength (4), and maintains its strength quite well compared to other materials, which implies that this material is preferred for wounds which are closed with tension. | ||
===Recovery=== | ===Recovery=== | ||
