20.20(S11):Advanced topics: Difference between revisions

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335–338 <br>[[PMID: 10659856]] <br>'''Construction of a genetic toggle switch in Escherichia coli'''<br> Gardner TS, et al.''Nature''(2000) 403, 339–342 <br>[[PMID: 10659857]]<br>
335–338 <br>[[PMID: 10659856]] <br>'''Construction of a genetic toggle switch in Escherichia coli'''<br> Gardner TS, et al.''Nature''(2000) 403, 339–342 <br>[[PMID: 10659857]]<br>
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|'''Protein Design'''<br>  
|'''Protein Design: directed evolution'''<br>  
| Wed Feb 23
| Wed Feb 23
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|'''De Novo Designed Proteins from a Library of Artificial Sequences Function in Esherichia Coli and Enable Cell Growth''' <br>Fisher MA, et al. ''PLoS One'' (2011)6(1):e15364<br>[[DOI: 10.1371/journal.pone.0015364]]
|'''De Novo Designed Proteins from a Library of Artificial Sequences Function in Esherichia Coli and Enable Cell Growth''' <br>Fisher MA, et al. ''PLoS One'' (2011)6(1):e15364<br>[[DOI: 10.1371/journal.pone.0015364]]
|'''Design of multi-specificity in protein interfaces'''Humphris, EL; Kortemme, T. ''PLoS computational biology'' (2007) 3(8):e164<br>[[DOI: 10.1371/journal.pcbi.0030164]]
|'''Directed evolution of recombinase specificity by split gene reassembly''' <br>Gersbach, CA, et al. ''NAR'' (2010) 38(12): 4198-4206-1543 <br> [[DOI: 10.1093/nar/gkq125]]
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| '''Tuning the system: directed evolution''' <br>
|'''RNA Engineering'''<br>
| Wed Mar 2
| Wed Mar 2
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|'''Directed evolution of recombinase specificity by split gene reassembly''' <br>Gersbach, CA, et al. ''NAR'' (2010) 38(12): 4198-4206-1543 <br> [[DOI: 10.1093/nar/gkq125]]
| '''Reprogramming Cellular Behavior with RNA Controllers Responsive to Endogenous Proteins'''<br>Culler, SJ, Hoff, KG, Smolke, CD. ''Science'' (2010) 330:1251-1255 <br>[[DOI: 10.1126/science.1192128]]
| '''A dual selection module for directed evolution of synthetic circuits.''' Yokobayashi Y, Arnold FH. ''Nat Comp'' (2005) 4:245–254<br>[[Media:DirEvolTuning NaturalComputing05.pdf| pdf]]
| '''The Case for RNA''' <br>Chang, CL, Arkin AP. ''Science'' (2010) 330:1185-1186<br>[[DOI: 10.1126/science.1199495]]  
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| '''RNA Engineering'''<br>  
| '''Tuning the system: Network Composition''' <br>  
| <font color = blue> Thursday Mar 10</font color>
| <font color = blue> Thursday Mar 10</font color>
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| '''Reprogramming Cellular Behavior with RNA Controllers Responsive to Endogenous Proteins'''<br>Culler, SJ, Hoff, KG, Smolke, CD. ''Science'' (2010) 330:1251-1255 <br>[[DOI: 10.1126/science.1192128]]
| '''A modular positive feedback-based gene amplifier''' Nistala GJ et al. ''JBE'' (2010) 4:4<br>[[DOI: 10.1186/1754-1611-4-4]]
|'''The Case for RNA''' <br>Chang, CL, Arkin AP. ''Science'' (2010) 330:1185-1186<br>[[DOI: 10.1126/science.1199495]]  
|'''A fast, robust and tunable synthetic gene oscillator''' <br>Stricker, J. et al. ''Nature'' (2008) 456, 516–519<br>[[PMID: 18971928]]
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| '''Tuning the system: Network Composition''' <br>  
| '''System Composition''' <br>  
| Wed Mar 16  
| Wed Mar 16  
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| '''A modular positive feedback-based gene amplifier''' Nistala GJ et. al. ''JBE'' (2010) 4:4<br>[[DOI: 10.1186/1754-1611-4-4]]
| '''Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA''' Warren L, et al. ''Cell Stem Cell'' (2010) 7:618-630<br>[[DOI:10.1016/j.stem.2010.08.012]]
| '''A fast, robust and tunable synthetic gene oscillator''' <br>Stricker, J. et al. ''Nature'' (2008) 456, 516–519<br>[[PMID: 18971928]]
| '''A fast, robust and tunable synthetic gene oscillator''' <br>Stricker, J. et al. ''Nature'' (2008) 456, 516–519<br>[[PMID: 18971928]]
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| Wed Mar 30
| Wed Mar 30
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| '''Article 1:''' <br>'''Programming cells by multiplex genome engineering and accelerated evolution'''<br>Wang HH, et al. ''Nature'' (2009) Aug 13;460(7257):894-8. <br>[[PMID: 19633652 ]]<br>'''Article 2:''' <br> '''Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome.'''Gibson DG, et al. Science. 2008 Feb 29;319(5867):1215-20. <br>[[PMID: 18218864]]
| '''Programming cells by multiplex genome engineering and accelerated evolution'''<br>Wang HH, et al. ''Nature'' (2009) Aug 13;460(7257):894-8. <br>[[PMID: 19633652 ]]
| '''Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides'''<br>Stemmer WP, et al. ''Gene'' (1995) 164(1):49-53 <br>[[PMID: 7590320]] <br>
| '''Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides'''<br>Stemmer WP, et al. ''Gene'' (1995) 164(1):49-53 <br>[[PMID: 7590320]] <br>
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