1,118
edits
Taylor: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
no edit summary
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
[[Image:Nucleation5.png|thumb|300px|right|Crystal nuclei in an amorphous drug]] | [[Image:Nucleation5.png|thumb|300px|right|Crystal nuclei in an amorphous drug]] | ||
The [http://www.ipph.purdue.edu/faculty/?uid=ltaylor Taylor] Lab is part of the [http://www.ipph.purdue.edu/ Department of Industrial and Physical Pharmacy]at [http://Purdue.edu/ Purdue University.]<br> | The [http://www.ipph.purdue.edu/faculty/?uid=ltaylor Taylor] Lab is part of the [http://www.ipph.purdue.edu/ Department of Industrial and Physical Pharmacy]at [http://Purdue.edu/ Purdue University.]<br> | ||
Our lab is interested in exploring the fundamental science underlying the preformulation, formulation and manufacturing of drugs and drug products. In general, our research interests are directed towards an improved molecular level understanding of pharmaceutical materials and formulations through the use of high resolution analytical techniques | Our lab is interested in exploring the fundamental science underlying the preformulation, formulation and manufacturing of drugs and drug products. In general, our research interests are directed towards an improved molecular level understanding of pharmaceutical materials and formulations through the use of high resolution analytical techniques. Of particular interest are water-solid interactions and disordered systems, especially amorphous solid dispersions. Vibrational spectroscopic methods, in conjunction with other techniques such as X-ray diffraction and calorimetry, are used to provide information about the physical state of the substance e.g. crystalline or amorphous, the response of the material to changes in temperature and relative humidity and the nature of drug-drug, drug-excipient and drug-water interactions. Recently, we have been using Raman spectroscopy to monitor phase changes during pharmaceutical processing operations in real time. | ||
