“Intravital imaging of naturally occurring Tregs in the thymus”
Brief description
In my project I will image naturally occurring Tregs inside a living thymus using a multi-photon microscope. The observation of cell-cell contacts between “wanna-be” Tregs and dendritic cells after different in vivo stimulation of thymocytes is a new approach to better understand nTregs generation.
“Effect of different types of Tregs in Experimental Autoimmune Encephalomyelitis (EAE)”
Brief description
Tregs are necessary to suppress the immune response against self-antigens. In my project I will compare the effect of MBP-specific Tregs versus Polyclonal-specific Tregs in the control of spontaneous EAE development and suppression of Th1/Th17 cells.
