Pan:Nathan Baird
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My research is aimed at understanding the structural basis of RNA
folding and stability. In the last decade, major advancements have been
made in the field of RNA crystallography, paving the way for
atomic-level understanding of what drives the folding of biologically
relevant RNAs. We use a wide variety of biophysical and biochemical
techniques to create models of RNA folding intermediates. Our most
recent work has involved electron cryomicroscopy and single particle
reconstruction to directly image the catalytic and specificity domains
of RNase P RNA.
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