Min-Ho Kim Lab

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Welcome to the Kim's research group at Kent State University

The major focus of research interests in our laboratory is to develop therapeutics to promote the resolution of non-healing chronic wounds based on precise understanding of inflammatory response to tissue injury and infection. Many non-healing chronic wounds have been associated with chronic inflammation. A more detailed understanding of mechanisms controlling the inflammatory response and how inflammation directs the outcome of the healing process will provide therapeutics for tissue repair in chronic inflammatory diseases. Our long-term goals are to (1) understand the molecular and cellular mechanisms by which local inflammatory environmental cues alter phenotypic switch of tissue infiltrating innate immune cells and these cells functionally interact with mesenchymal stem cells, and (2) develop selective strategy to engineer microenvironmental cues towards tissue regeneration by utilizing micro/nano-engineered biomaterials that enable spatio-temporal control of inflammatory response. To achieve this goal, we combine interdisciplinary approaches of immuno-biology, stem cell biology, cellular and tissue engineering, and nano-bioengineering.

Featured News

  • May 2022, Kim lab is awarded with a NIH R01 grant from NIA for investigating magneto-thermal brain stimulation towards the rescue of beta-amyloid pathology, as a potential therapeutic for Alzheimer's disease.
  • February 2021, Kim lab's research on the development of new synthetic antimicrobial compound to overcome the development of drug resistance is featured [Link here for more info]
  • January 2021, Kim lab is awarded with a Brain Health Research Institute (BHRI) pilot grant to validate mild magnetic nanoparticle hyperthermia as a strategy to target amyloid beta plaques in animal model of Alzheimer's disease.
  • November 2020, Kim lab is awarded with TeCK Fund grant to develop topical antimicrobial creams towards the treatment of skin and soft tissue MRSA infections.
  • September 2018, Kim lab is awarded with a new NIH supplement grant to pursue a project to develop targeted magnetic nanoparticle hyperthermia that can target amyloid beta plaques towards the treatment of Alzheimer's disease.
  • June 2017, Jess Krieger is awarded with a research fellowship from New Harvest. Congratulation for the achievement.
  • April 2015, Kim lab is awarded with a NIH R01 grant from NINR to pursue a project to develop non-invasive magnetic nanothermotherapy platform for the treatment of wound biofilm infection.[Link here for more info]