. 12/2017: Jiejun and Jie's collaborative papers with Xiaobing Shi were accepted to Genes & Development and Nature Communications, respectively
. 09/2017: Feng Xin and Lei Li's paper on TC3A: The Cancer 3’ UTR Atlas was accepted to Nucleic Acids Research.
. 09/2017: Hyun Jung Park has been offered a tenure-track Assistant Professor position at University of Pittsburgh Medical Center. Congratulations.
. 08/2017: Xueqiu's scUMC DNA methylation paper was accepted to Genome Biology.
. 07/2017: Jianzhong's DNA methylation editing papers with the Goodell lab were published in Nature Communications and Genome Biology.
. 05/2017: Our TCGA Liver Cancer paper was accepted to Cell.
. 02/2017: Our Research Center for Cancer Systems Biology (CCSB U54) grant was funded by NCI, in collaboration with Qianben Wang, Victor Jin and Tim Huang.
. 02/2017: Collaborative work with Xiaobing Shi and David Allis was accepted to Nature.
. 12/2016: Graduate student Xueqiu Lin will start his postdoc position at Stanford.
. 11/2016: Jianfeng Xu has passed his qualify exam. Congratulations!
. 08/2016: Welcome our new Postdoc Associates Drs. Xiaodong Cui, Jiejun Shi and Lei Li.
. 08/16: Zheng Xia will start his tenure-track faculty position at Oregon Health & Science University (OHSU) with a million-dollar package. Congratulations!
. 07/16: Wei has been promoted to Professor of Bioinformatics at Baylor College of Medicine.
. 06/16: Xueqiu successfully defended her PhD thesis. Congratulations Dr. Lin.
. 06/16: A new paper w/ MG Lee @ MD Anderson was accepted to Molecular Cell.
. 04/16: Jianzhong's DNMT3A/TET2 paper (w/ Goodell lab) was accepted to Nature Genetics.
. 04/16: Wei has been selected as a recipient of the 2016 Michael E. DeBakey, M.D., Excellence in Research Award
. 04/16: Yuanxin has been offered a tenure-track faculty position at The University of Texas Health Science Center at Houston (UTHealth). Congratulations!
. 03/2016: Ben's enhancer hypomethylation paper (w/ Goodell lab) was accepted to Cancer Cell.
. 02/2016: Yuanxin's SIRT6 paper (w/ Chua lab at Stanford) was accepted to Nature Structural & Molecular Biology
. 01/2016: Welcome our new Postdoc Associate Dr. Jie Lyu.
. 12/2015: Yuanxin's G9a paper (w/ Shi lab at MD Anderson) was accepted to Nature Communications.
. 12/2015: Kaifu's UTX paper (w/ Lee lab at MD Anderson) was accepted to Nucleic Acids Research .
. 11/2015: We received a new NIH/NCI R01 grant (scored at 5%ile) to study 3`UTR alternations in human cancers.
. 09/2015: Welcome our new Research Associate (and potential Graduate Student) YanBing Cheng.
. 08/2015: Kaifu's Cancer Big-data analysis paper is published in Nature Genetics. This work links broad H3K4me3 to pan-cancer tumor suppressors. See reports in Nature Editor’s Blog, Cancer Discovery, ebiotrade.com (in Chinese), BCM news and OSU news; and an error we found in a Cell paper.
. 07/2015: Wei will become a regular member of the NIH GCAT (Genomics, Computational Biology and Technology) study section.
. 06/2015: Kaifu will start his tenure-track faculty position at Cornell University & Methodist Hospital. Congratulations!
. 03/2015: Kaifu's MeCP2 mCH binding paper (w/ Zoghbi lab) is accepted to PNAS.
. 3/2015: We received a NEW CPRIT grant.
. 01/2015: Deqiang, HJ and Ben's HSC novel noncoding RNA paper is accepted to Cell Stem Cell -- the 100th paper we published.
. 12/2014: Zheng Xia is awarded a Keck fellowship in Computational Cancer Biology.
. 11/2014: Zheng's DaPars 3'UTR Pan Cancer analysis paper is published in Nature Communications.
. 09/2014: Liguo's ChIP-exo methodology paper (MACE) is accepted to Nucleic Acids Research. MACE is recommended by Active Motif as the software solution for the company's new ChIP-exo kit and service.
. 09/2014: Deqiang will start his tenure-track assistant professor position. Job well done.
. 09/2014: Zheng's prostate cancer RNA-seq paper with Dr. Balk at Harvard is accepted to Molecular Cancer Research .
. 09/2014: Yuanxin's work on H3K79 Methylation with Dr. Shi is accepted to Cell.
. 08/2014: Three Collaborative CPRIT grants are funded: DNA methylation with Goodell lab, 3'UTR with Wagner lab and ZM11 with Shi lab.
. 06/2014: Deqiang's Dnmt3a/3b double KO paper (w/ Goodell Lab) is accepted to Cell Stem Cell .
. 06/2014: Zheng's alternative splicing paper (w/ Cooper Lab) is accepted to Molecular Cell .
. 02/2014: Zheng's brain tumor 3'UTR regulator paper is accepted to Nature. This paper was initially rejected after review twice. We appealed twice with success and finally made it in the 3rd submission.
. 02/2014: Welcome our new postdoc Jianzhong Su and graduate student Xueqiu Lin.
. 02/2014: Deqiang's mouse HSC Aging Epigenomics paper is accepted in principle to Cell Stem Cell.
. 01/2014: Deqiang's Methodology paper for the detection of differential DNA Methylation (MOABS) is accepted to Genome Biology.
. 01/2014: Yuanxin and Zheng's ZM11 paper with Xiaobing Shi lab in MD Anderson is accepted to Nature. This work links transcription elongation to tumor suppression.
. 12/2013: Kaifu's aging nucleosome paper is accepted to Genes & Development
. 12/2013: We received a 5-year NIH/NHGRI R01 grant (scored at 6 percentile in its first submission) to study DNA Methylation
. 11/2013: Wei will serve on the Editorial Board of Molecular Endocrinology
. 09/2013: Deqiang's DNA methylation Canyon paper is accepted to Nature Genetics.
. 09/2013: Xueqiu's bisulfite sequencing quality control paper (BSeQC) is accepted to Bioinformatics.
. 08/2013: Kadir's p53 paper is accepted to Nucleic Acids Research
. 12/2012: Liguo and HJ's CPAT RNA coding potential prediction paper is accepted to Nucleic Acids Research.
. 11/2012: Kaifu's nucleosome methodology paper DANPOS is accepted to Genome Research.
. 10/2012: Kaifu's promoter nucleosome paper is accepted to Genome Research.
. 09/2012: A NIH R01 grant was funded. We will work with Dr. Issa at Temple Univ. to understand DNA methylation in Cancer.
. 08/2012: A mouse ES nucleosome paper from Kaestner lab at Upenn is accepted to Cell. Kaifu and Wei used DANPOS to analyze the data and were listed as co-authors.
. 08/2012: Dr. Benjamin Rodriguez will join us as a Postdoc Associate. Ben has PhD in Integrated Biomedical Science from the Ohio State Univ. Welcome!
. 08/2012: A Mazzone Award is funded. We will work with Dr. Balk at Harvard Medical School to understand the molecular features of aggressive prostate cancer.
. 06/2012: Liguo's RNA-seq Quality Control paper is accepted to Bioinformatics.
. 06/2012: A NIH R01 grant is funded. We will work with Dr. Goodell at BCM to understand DNA methylation in Hematopoietic Stem Cell.
. 04/2012: A NIH R01 grant is funded. We will work with Dr. Dent at MD Anderson to define USP22 functions during mammalian development.
. 04/2012: Dr.Dean Tang's prostate cancer stem cell paper is accepted in Cell Stem Cell. Wei is a co-author.
. 02/2012: Yuanxin's epigenetic paper with Katrin Chua lab at Stanford is accepted to Nature. Two years of hard work finally paid off!
. 02/2012: Liguo Wang is offered a tenure-track Assistant Professor position at Mayo Clinic. Congratulations!
. 02/2012: Justin Park will join us as a Postdoc Associate. Justin will graduate in May with a PhD in Computer Science from Rice University. Welcome!
. 11/2011: Yuanxin's RRBSMAP paper was accepted to Bioinformatics.
. 09/2011: Wei Li was promoted to tenured Associate Professor at BCM. Cheers!
. 09/2011: Deqiang's DNA methylation paper with Peggy Goodell lab was accepted to Nature Genetics.
. 08/2011: Kaifu's NSD2 epigenetic paper with Or Gozani lab at Stanford was accepted to Molecular Cell.
. 08/2011: A NIH R01 grant was funded. We will work with Dr. Wang at the Ohio State University to understand the role of histone methylations in prostate cancer.
. 07/2011: Liguo's FoxA1 cistrome paper was accepted to Cancer Research.
. 07/2011: See our Genomic Regulation Technical Guide on Genome Technology magazine
. 07/2011: Dr. Zheng Xia will join us as a postdoc fellow. Zheng has PhD in Control Theory and Engineering Computer Science from Zhejiang University in China. Welcome!
. 05/2011: Dr.Bert O'Malley's coregulator network paper was published in Cell. Wei is a co-author on the paper.
. 04/2011: Liguo's Prostate Cancer RNA-seq paper was officially accepted to PNAS.
. 03/2011: Our Texas CPRIT Multi-Investigator grant was funded with a total direct cost of ~$10M for 5 years. This project will bring together a "dream team" in cancer epigenetic research. We will direct the bioinformatics component for LONESTAR.
. 01/2011: Yuanxin's fragile nucleosome paper was accepted to Genome Research.
. 01/2011: Yuanxin and Liguo's Atoh1 targetome paper was accepted to PNAS.
. 12/2010: Liguo's fly RNA-seq paper was published in Genome Research.
. 10/2010: A Texas CPRIT grant was funded. We will work with Dr. Goodell at BCM to understand DNA Methylgransferase 3B in normal and malignant hematopoiesis.
. 08/2010: Our Pilot Project was funded by a NIH Stem Cell P01 Grant.
. 07/2010: The DNA methylation platform comparision paper was accepted to Nature Biotechnology.
. 06/2010: Hao Zhao will join us as a postdoc fellow. Hao has a PhD in Computer Science from City University of Hong Kong. Welcome!
. 05/2010: Our paper titled "Histone modifications and chromatin organization in prostate cancer" has been accepted by Epigenomics.
. 01/2010: A Texas CPRIT grant has been funded. We will use ChIP-seq and RNA-seq to analyze Androgen Receptor (AR) function in Prostate Cancer with Dr. Weigel at BCM.
. 01/2010: Wei Li is an invited speaker in the American Association for Cancer Research (AACR) Special Conference on Cancer Epigenetics at Puerto Rico.
. 01/2010: Deqiang Sun will join us as a postdoc fellow. Deqiang has a PhD in Condensed Matter Physics from Texas A&M University. Welcome!
. 12/2009: Dr.Bert O'Malley's SRC-3 ChIP-seq paper has been accepted by Molecular Endocrinology. Liguo and Wei are co-authors on the paper.
. 12/2009: Liguo's RNA-seq methodology paper has been accepted by PLoS ONE. Congratulations Liguo!
. 11/2009: Wei Li received a New Investigator Award from the Department of Defense (DOD) Prostate Cancer Research Program (PCRP). Cheers!
. 11/2009: Wei Li gave a Keynote Presentation at the Symposium on Advances in Cell Signaling, Cancer Prevention and Therapy at South Padre Island, Texas.
. 09/2009: A prestigious NIH Challenge grant has been funded. We will use ChIP-seq to analyze RXRa binding in mouse liver with Dr. Karpen at Texas Children's Hospital.
. 09/2009: A two-year $2.5 million NIH Grand Opportunity (GO) grant has been funded. We will study aging epigenomics with Drs. Darlington and Goodell at BCM.
. 09/2009: A prestigious NIH Challenge grant has been funded. We will use RNA-seq to characterize patient cardiac progenitors with Dr. Pu at Harvard Medical School.
. 06/2009: Yuanxin's Bisulfite Sequence Mapping paper has been accepted by BMC Bioinformatics. Congratulations Yuanxin!
. 06/2009: Kaifu Chen has accepted our postdoc offer. Kaifu has a PhD in Genomics and Bioinformatics from Beijing Institute of Genomics, Chinese Academy of Sciences. Welcome!
. 03/2009: Wei's paper titled 'Reprogrammed Androgen Receptor Function in Androgen-Independent Prostate Cancer' has been accepted by Cell.
. 03/2009: Cancer Epigenomics Workshop Please join us on May 2nd 2009 at MD Anderson Cancer Center. This meeting is organized by Steffi Oesterreich, Wei Li and Jean-Pierre Issa.