Imperial College/Courses/Fall2008/Synthetic Biology (MRes class)/Resources/Literature

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General Reviews on Synthetic Biology

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2. Endy D. Foundations for engineering biology. Nature. 2005 Nov 24;438(7067):449-53. DOI:10.1038/nature04342 |
3. Andrianantoandro E, Basu S, Karig DK, and Weiss R. Synthetic biology: new engineering rules for an emerging discipline. Mol Syst Biol. 2006;2:2006.0028. DOI:10.1038/msb4100073 |

Seminal Papers

• 'Cellular Gate Technology', 1998, Knight, Thomas F. Sussman, Gerald Jay
• 'A Standard Parts List for Biological Circuitry', 1999, Arkin, Adam Endy, Drew
• 'Cellular computation and communications using engineered genetic regulatory networks', 2001, Ron Weiss

1. Elowitz MB and Leibler S. A synthetic oscillatory network of transcriptional regulators. Nature. 2000 Jan 20;403(6767):335-8. DOI:10.1038/35002125 |
2. Gardner TS, Cantor CR, and Collins JJ. Construction of a genetic toggle switch in Escherichia coli. Nature. 2000 Jan 20;403(6767):339-42. DOI:10.1038/35002131 |

Cool/Inspiring Synthetic Biology Projects

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1. Chan LY, Kosuri S, and Endy D. Refactoring bacteriophage T7. Mol Syst Biol. 2005;1:2005.0018. DOI:10.1038/msb4100025 |
4. Anderson JC, Clarke EJ, Arkin AP, and Voigt CA. Environmentally controlled invasion of cancer cells by engineered bacteria. J Mol Biol. 2006 Jan 27;355(4):619-27. DOI:10.1016/j.jmb.2005.10.076 |
5. Lu TK and Collins JJ. Dispersing biofilms with engineered enzymatic bacteriophage. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11197-202. DOI:10.1073/pnas.0704624104 |

Expression Chassis Related

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DNA Assembly Related

1. Idempotent Vector Design for Standard Assembly of Biobricks, Knight T. et al (2003)
2. A New Biobrick Assembly Strategy Designed for Facile Protein Engineering, Phillips, Silver (2006)

Modelling Related

• Dynamics and Control of Synthetic Bio-molecular Networks (Del Vecchio and Sontag, 2007)
• Modular cell biology: retroactivity and insulation (Del Vecchio et al, 2007)
• An Introduction to Systems Biology (Uri Alon)

Synthetic Biology: Ethics and Impact on Society

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