IGEM:Stanford/2009/Project Homeostasis/Experimental Archives

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Project
Research Proposal
Systems Overview
Cloning Plan
Sequences & Primers
Anti-Inflammation
Device Overview
Parts Design
Challenges
Results
Anti-Immunosuppression
Device Overview
Parts Design
Challenges
Results
Protocols
Modeling
Overview
Notebook
Results
Future Work
Archived Work



System Overviews



Inflammation Device

Goal: To design the device that monitors and responds to inflammation.

  • a. Input: a promoter that monitors inflammation by detecting levels of Th17-derived markers.
  • b. Output: a gene that responds to inflammation by inhibiting the Th17 response and enhancing the Treg lineage.
  • Anti-Inflammatory Device (Developed So Far)
Device 1

Immunosuppression Device

Goal: To design the device that monitors and responds to immunosuppression.

  • c. Input: a promoter that monitors immunosuppression by detecting levels of Treg-derived markers.
  • d. Output: a gene that responds to Treg-driven immunosuppression by inhibiting the Treg response and enhancing the Th17 lineage.
  • Immunosuppression Device (Developed So Far)
Device 2

Discussion

Paper Pages

  • PLoS. Role of IL-6 in mice.

Primer Design

Gene Sequences and Orders

Trp Repressor Analogue

Parts