Catherine Channell - Dahlquist Lab

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Catherine Channell

Spring 2021

Week 3

1/29

Week 4

2/2

  • complete tutorial assignment on openwetware

2.5

Summer 2021

Week 1

5/19 @1-2 PM: Meeting w/Dr. Dahlquist

  • OpenWetWare Tasks

Week 2

5/26 @1-2 PM: Meeting w/Dr. Dahlquist

  • Add image, pdf, template, and fix Service and Leadership section

5/26 @2:30-6:30 PM: Meeting w/Claire

  • Article Searches 2020-2021 using 'lactase persistence frequency' at https://pubmed.ncbi.nlm.nih.gov/
    • Anguita-Ruiz, A., Aguilera, C. M., & Gil, Á. (2020). Genetics of Lactose Intolerance: An Updated Review and Online Interactive World Maps of Phenotype and Genotype Frequencies. Nutrients, 12(9). https://doi.org/10.3390/nu12092689
      • Created two online interactive resources, which constitute an upgrade over previously published static world maps, and allow users a personalized data exploration, while at the same time accessing complete reports by population or ethnicity
    • Fung, M., Xue, X., & Szilagyi, A. (2020). Estimating Lactase Nonpersistence Distributions in the Multi-Ethnic Canadian Demographic: A Population-Based Study. Journal of the Canadian Association of Gastroenterology, 3(3), 103–110. https://doi.org/10.1093/jcag/gwy068
      • Used the latest 2016 population census into our sampled population and used Storhaug data of global LNP prevalence to derive LNP estimation rates for the Canadian demographic
    • Hollfelder, N., Babiker, H., Granehäll, L., Schlebusch, C. M., & Jakobsson, M. (2021). The genetic variation of lactase persistence alleles in Sudan and South Sudan. Genome biology and evolution, evab065. Advance online publication. https://doi.org/10.1093/gbe/evab065
      • Research paper that collected/sequenced frequencies of genetic variants linked to LP in Sudanese and South Sudanese populations
    • Dewiasty, E., Setiati, S., Agustina, R., Roosheroe, A. G., Abdullah, M., Istanti, R., & de Groot, L. C. (2021). Prevalence of lactose intolerance and nutrients intake in an older population regarded as lactase non-persistent. Clinical nutrition ESPEN, 43, 317–321. https://doi.org/10.1016/j.clnesp.2021.03.033
      • data on the prevalence of lactose intolerance and dietary intakes in Indonesian older outpatients based on a hydrogen breath test
  • no additional articles using 'lactase persistence population' at https://pubmed.ncbi.nlm.nih.gov/
  • no additional articles using 'lactase persistence' at https://pubmed.ncbi.nlm.nih.gov/
  • articles using 'lactase persistence' at http://apps.webofknowledge.com.electra.lmu.edu/WOS_GeneralSearch_input.do?product=WOS&search_mode=GeneralSearch&SID=8Fzg1zagUWiBD6DBnTk&preferencesSaved=
    • Jacobs, E. T., Foote, J. A., Kohler, L. N., Skiba, M. B., & Thomson, C. A. (2020). Re-examination of dairy as a single commodity in US dietary guidance. Nutrition Reviews, 78(3), 225–234. https://doi.org/10.1093/nutrit/nuz093
      • Following Canada's removal of lactose as a separate food group for national dietary guidelines, a suggestion on why the US should think about doing the same
  • no additional articles using 'lactase persistence' at https://search-sciencemag-org.electra.lmu.edu/?searchTerm=lactase%20persistence&order=tfidf&limit=textFields&pageSize=10&startDate=2020-01-01&endDate=2021-06-01&&
  • articles using 'lactase persistence frequency' at https://scholar.google.com/
    • Борозенець, В. В., Бабалян, В. О., & Федота, O. M. (2020). Genetiс aspects of lactase persistence in different ethnic groups. Фактори експериментальної еволюції організмів, 27, 185-189.
      • lactase persistence frequencies in different European ethnic groups (Ukrainian, Indian, Nigerian, Israeli, Egyptian, Palestinian, Turkish, Jordanian students (n=361) and their relatives of the first degree of kinship (n=413))
    • Ramadan, M., Eid, A. M., Seliem, N. M., & Shokr, H. A. (2020). Assessment of lactose intolerance in adult Egyptian patients with dyspeptic symptoms using lactase enzyme assay in duodenal biopsy. The Scientific Journal of Al-Azhar Medical Faculty, Girls, 4(2), 300.
      • Study of the severity of lactose-intolerance symptoms in Egyptian patients
    • Ojeda-Granados, C., Panduro, A., Rivera-Iñiguez, I., Sepúlveda-Villegas, M., & Roman, S. (2020). A Regionalized Genome-Based Mexican Diet Improves Anthropometric and Metabolic Parameters in Subjects at Risk for Obesity-Related Chronic Diseases. Nutrients, 12(3), 645.
      • Provides an implemented example of how taking into account LNP can result in a healthy, balanced diet
    • Mørk, M., Andersen, S. L., Pedersen, I. S., Ernst, A., Lykkeboe, S., & Krarup, H. B. (2020). Use of genetic testing for hypolactasia trait in the North Denmark region. Scandinavian Journal of Gastroenterology, 55(9), 1012-1018.
    • Martínez Rodríguez, M., Samaniego-Vaesken, M., & Alonso-Aperte, E. (2021). A New Food Composition Database of Lactose-Free Products Commercialized in Spain: Differences in Nutritional Composition as Compared to Traditional Products. Foods, 10(4), 851.

Week 3

6/2 @1-2 PM: Meeting w/Dr. Dahlquist

  • Read Review Article on World Maps
  • Read Segurel, L., Guarino-Vignon, P., Marchi, N., Lafosse, S., Laurent, R., Bon, C., Fabre, A., Hegay, T., & Heyer, E. (2020). Why and when was lactase persistence selected for? Insights from Central Asian herders and ancient DNA. PLOS Biology, 18(6), e3000742. [1]
  • Journal club on Canadian study
    • 1+ intro slides
    • titles as messages
    • figure and tables each get their own slide
    • conclusion

6/2 @2-6 PM: Meeting w/Claire

Week 4

6/2 @1-2 PM: Meeting w/Dr. Dahlquist

  • Read Review Article on World Maps
  • Read Storhaug et. al

6/2 @2-6 PM: Meeting w/Claire

Week 5

6/16 @1-2 PM: Meeting w/Dr. Dahlquist

  • approach for paper will be review of genetic information available for U.S. on different databases
  • start with Ensemble and 13910
    1. individuals in pop. sampled, where they are from/ethnicity, & traceable data needed in order to avoid duplication of studies

6/17 @2:30-6:30 PM: Meeting w/Claire

  • Smith et. al (2016) to 2002

Week 6

6/23 @1-2 PM: Meeting w/Dr. Dahlquist

  • Send dbSNP email about criterion for 89 publications
  • Finish checking publications
  • Add reason why exlcuded
  • General Summary of Data Once all Sorted Through


Week 7

6/30 @1-2 PM: Meeting w/Dr. Dahlquist

  • 2-5 page summary of work to date

Week 8

7/7 @1-2 PM: Meeting w/Dr. Dahlquist