Biomod/2015/UTokyo-Komaba:PROJECT

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Introduction

When original chemical batteries were invented by Volta, Italian physicist in 1800, history of batteries started and have been developing.
Even today, we use various types of batteries such as a dry battery or a fuel battery.

In a number of batteries, we are paying attention to a battery to implant a bio fuel battery in living body.
Many battery-powered implantable medical devices were developed for treatments, ranging from neurological disorders to hearing loss.(※1)

In the current study, Cosnier and co-workers, in cooperation with the Cinquin's group, implanted a new bio fuel battery design(※2)into rat.
However, this research is not yet able to implant bio fuel battery into blood vessels, because positioning a battery in a blood vessel requires “hemocompatibility" ,which is more challenging than “biocompatibility” i.e. no rejection or immune response from the body.(※3)

Here we propose to make a new device made of liposome for bio fuel batteries. The device is expected to adapt to human body because liposome have a property of biocompatibility ,which is often used in drug delivery system.


※1,2,3:Serge, C. Alan, L, G. Michael ,H.(2014) Towards glucose biofuel cells implanted in human body for powering artificial