BioControl:Week5

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Next meeting Friday, 1/19 at 9am in 110 Steele Topics Bacterial Chemotaxis Perfect adaptation Amplification Reading Error fetching PMID 9202124 Error fetching PMID 16446460 Discussion The cells are selecting for noisy function[3], but too much noise (particularly with extreme amplification) would seem to be a problem. If you could specify everything in this system, where would you want noise? Drunken random walks seem to be a common solution to this kind of problem - why? It looks to me (Jkm) like a good way to deal with noisy inputs. Is there more to it? Are there better (engineering?) ways of solving the same problem? Going from experiments to models (particularly in biology) - are assumptions (CheB only demethylates active receptors) good, since they give us testable hypotheses? Or bad, since they're just artificial constraints in order to get the 'right' answer? Further Reading Error fetching PMID 9923680 Error fetching PMID 9207079 Error fetching PMID 12232047 Error fetching PMID 11742065 Error fetching PMID 10698740 Error fetching PMID 15569922 Error fetching PMID 15058306 Error fetching PMID 10781070