BioControl:Week2-22

Home Members Best of 2006-2007 Best of 2007-2008 Past Reading Changes

Next meeting 4/29 at 10:30am in the Steele library. Topics Delays in gene regulation Reading Bratsun D, Volfson D, Tsimring LS, and Hasty J. Delay-induced stochastic oscillations in gene regulation. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14593-8. DOI:10.1073/pnas.0503858102 | Related Articles Without any real consequence to the paper, it has been shown that the delayed Gillespie algorithm they present is not correctly derived. The error is fairly insignificant, and a correct algorithm requires only a tiny correction. So if you ever go to implement something like this, take a glance the paper below, which is poorly communicated but mathematically rigorous: Cai X. Exact stochastic simulation of coupled chemical reactions with delays. J Chem Phys. 2007 Mar 28;126(12):124108. DOI:10.1063/1.2710253 | Discussion