BioControl:Week2-22

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Best of 2006-2007

Best of 2007-2008

Past Reading

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Next meeting

  • 4/29 at 10:30am in the Steele library.

Topics

  • Delays in gene regulation

Reading

  1. Bratsun D, Volfson D, Tsimring LS, and Hasty J. Delay-induced stochastic oscillations in gene regulation. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14593-8. DOI:10.1073/pnas.0503858102 | PubMed ID:16199522 | HubMed [bratsun05]


Related Articles

Without any real consequence to the paper, it has been shown that the delayed Gillespie algorithm they present is not correctly derived. The error is fairly insignificant, and a correct algorithm requires only a tiny correction. So if you ever go to implement something like this, take a glance the paper below, which is poorly communicated but mathematically rigorous:

  1. Cai X. Exact stochastic simulation of coupled chemical reactions with delays. J Chem Phys. 2007 Mar 28;126(12):124108. DOI:10.1063/1.2710253 | PubMed ID:17411109 | HubMed [cai07]

Discussion