BioControl:Week2-12

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Next meeting Wednesday, 2/6 at 10am in the Steele library. Topics Unraveling network topology and the phenotypic consequences in a MAPK pathway Reading Santos SD, Verveer PJ, and Bastiaens PI. Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate. Nat Cell Biol. 2007 Mar;9(3):324-30. DOI:10.1038/ncb1543 | Related Articles Kholodenko BN. Untangling the signalling wires. Nat Cell Biol. 2007 Mar;9(3):247-9. DOI:10.1038/ncb0307-247 | Kholodenko BN, Kiyatkin A, Bruggeman FJ, Sontag E, Westerhoff HV, and Hoek JB. Untangling the wires: a strategy to trace functional interactions in signaling and gene networks. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12841-6. DOI:10.1073/pnas.192442699 | Discussion