BME100 s2016:Group1 W1030AM L2
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LAB 2 WRITE-UP
Based off of the ANOVA test, it was shown that at least two of the human data sets were statically significant. To further test the data, the Bonferroni Correction was employed and it was found that in fact all 6 sets had statistically significance. The rat trial was shown to have no significance based off of the P-Test.
From the statistical analysis of the data given, it was found that for the human trial, LPS affected the levels of inflammation in the body depending on the dosage (0mg, 5mg, 10mg, and 15mg). It was found that the highest dosage of LPS caused the highest amount of inflammation to be found in the body - the 15mg dose, on average lead to 657.941pg/ml. In the rat trial, the dosage has no statistical significance on the levels of inflammation in the rats. While it appears that the drug has no effect on rats, human trials showed different results. Based off of the results of the humans trials, which showed there was a significant difference between the dosages, it can be assumed that smaller dosages do in fact reduce inflammation in humans. It appears that 10 mg dosage had a large effect while 5 mg and less did not show significant reduction in inflammation. From the data, a 10 mg dosage is the smallest that can significantly reduce inflammation in most people.