BME100 s2016:Group11 W1030AM L2
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LAB 2 WRITE-UP
We did two experiments in order to investigate the effect of LPS to increase inflammotin on human. And one of the two we choose rat as object for a preclinical test. We only chose two groups of rats who are injected 0 mg and 10 respectively. according to the acquired data, the average of two groups' inflammation level are very close, but the 10mg group' SD is very high, after t-test, we found out that there isn't a statistically difference of the effect of different dose of LPS on rat. For the experiment on human, we had 4 groups given 0,5,10,15 mg LPS separately. The inflammotin level increased greatly with increased dose of LPS, and corresponding SD of each group also increase greatly. Through one-way ANOVA, we got very low p-value which prove the result is accurate and stable and that LPS can increase the inflammotin level in human body. Finally, we think the failure of LPS on rats and success on human may give might be contributed to the large number of objects and groups on human experiment, or it's because the difference between human and rat themselves that lead to opposite experiment results.