BME100 s2015:Group6 12pmL1
BME 100 Spring 2015 | Home People Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3 Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6 Course Logistics For Instructors Photos Wiki Editing Help | |||||
OUR TEAMLAB 1 WRITE-UPWhat is the lowest possible dose of lipopolysaccharide (LPS) that can increase Inflammotin levels in the elderly? Independent and Dependent VariablesIndependent Variable- Lipopolysaccharide (LPS) Dependent Variable- Inflammotin Experimental DesignGroups 0mg of LPS 10 mg of LPS
Dosage of LPS for the 9 experimental groups: 1mg of LPS 2mg of LPS 3mg of LPS 4mg of LPS 5mg of LPS 6mg of LPS 7mg of LPS 8mg of LPS 9mg of LPS
-Groups will be 5 male and 5 female -Aside from gender, all subjects will be randomly chosen in terms of race, age (within the 70-75 range), cultural background, etc.
Subject Selection-All subjects must be 70-75 years old -Should have a similar health history, but otherwise diverse (race, culture, gender, etc) -Patients should not already have inflammation issues or be taking anti-inflammatory drugs
Sources of Error and BiasError: Health history and previous medical conditions may affect how subject's body reacts to LPS Solution: Must select test subjects without inflammation issues and of similar health history
Solution: Ensure subjects are not currently taking anti-inflammatory medicines and that their other medications will not interfere with test results
Solution: Select as diverse of a test group as possible
Solution: Choose subjects with similar body compositions
Error: Using the same test group could produce biased Inflammotin levels due to residual LPS in the system from previous trial Solution: Each trial uses a different group of test subjects
Error: Test subjects may have different baseline levels of Inflammotin prior to receiving LPS Solution: Select subjects that had similar baseline levels
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