David Lowry
About Me
I am a fourth year graduate student in the Duke University Program in Genetics and Genomics, who hails from the redwood empire and wine country of Northern California. I spent 4.5 years of long latte-drinking nights at UC Berkeley during the thrilling boom and crash of the dot-com era. After college, I set out to explore the finer delights of world cultures and wildlife before joining the grind of graduate school. Alas, my time at Duke has been good to me thanks to many fantastic people and my amazingly optimistic leader/advisor, Dr. Johh Willis.
The focus of my research is directed toward understanding the genetics of adaptation and speciation. To this end, I have chosen to study how divergent adaptation of the yellow monkey flower (Mimulus guttatus), to the coast versus inland habitat, contributes to reproductive isolation. I am using a combination of QTL mapping, candidate gene strategies, and microarrays to determine the genetic mechanisms that underlie the divergence of morphological and life-history traits between coast and inland Mimulus guttatus. Further, I have carried out reciprocal transplant experiments and population genetic analysis to demonstrate that coast and inland Mimulus are locally adapted and reproductively isolated. I am currently creating near isogenic lines, with QTLs of large effect, for field experiments to test hypotheses of adaptation and ecogeographic reproductive isolation.
Publications
Lowry, D. B., M. C. Hall, J. H. Willis. Polymorphism and fixation of adaptive loci between coast and inland races of Mimulus guttatus. In prep
Wu, C. A., D. B. Lowry, L. I. Nutter, J. H. Willis. Natural variation for drought response in the Mimulus guttatus species complex. In prep
Lowry, D. B., R. C. Rockwood, J. H. Willis. (2008). Ecological reproductive isolation of coast and inland races of Mimulus guttatus. In press Evolution
Important Things
- Contact Info: You can contact me at david.lowry@duke.edu.
- Make sure to check out the Mimulus Community.
- See the relationship of coast and inland populations as determined by neutral microsatellite loci.
- Treat your fears with Mimulus.
Blog Roll
Bioinformatic/Statistical Software and Resources
- Bonferroni Correction Calculator
- Apollo
- sim4
- BLAT
- NCBI Trace Archives
- ClustalW
- Primer 3
- Q-Value calculator
Population Genetic Software
- TESS
- FSTAT
- Tassel
- Arlequin
- Structure
- Mark Beaumont
- Geographic distance matrix generator
- Genepop (web)
- Dyerlab (Population Graphs)
- Isolation by Distance
- Genetic Data Analysis
- Software for Populaiton Genetic Analysis
- Ian Wilson (Batwing)
- Jody Hey (SITES)
- Structurama
- DNASP
- SNAP
Analysis of fitness data
Abiotic Stress Websites
Other useful sites
- Blank Outline Maps that can be used to make figures.
Field Sites
United States
- Copperopolis
- Montana de Oro State Park
- Big Creek Reserve
- Bodega Marine Lab
- Angelo Reserve
- Redwood National Park
- Saddle Mountain
Canada
Friends on OWW
Quotes
"There is keen delight in the quick experience, of knowing that no harm comes of a wetting at high canon wall, slips up behind the ridge to cross it by some windy broad-leaved hellebore, and beat down the mimulus beside the brook." -Mary Austin