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1. Exemplar graduate project: molecular physiology of L-type Ca2+ (CaV1)channels

a. Excitation-transcription coupling by CaV1 signaling in neurons

b. Design of specific modulators of CaV1 subtypes

2. Exemplar graduate project: innovative quantitative Fluorescence Resonance Energy Transfer (FRET) imaging

a. Design and characterizations of genetically-encoded probes/sensors for key biological signals

b. Innovative platform of probe/imaging system/algorithm to expand 33-FRET to microscopic and macroscopic imaging