Warren Tourtellotte

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Contact Info

Associate Professor, Pathology (Neuropathology), Neurology and Neuroscience
Director, Mouse Histology and Phenotyping Laboratory, Feinberg School of Medicine

Northwestern University
Feinberg School of Medicine
Department of Pathology
Ward Building 7-112
303 E. Chicago Ave.
Chicago, IL 60611
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  • Year, PhD, Institute
  • Year, MS, Institute
  • Year, BS, Institute

Research interests

  • Animal Models of Human Disease
  • Neuroscience
  • Development
  • Chromatin Structure/Gene Expression

Select Publications

  1. Eldredge LC, Gao XM, Quach DH, Li L, Han X, Lomasney J, and Tourtellotte WG. Abnormal sympathetic nervous system development and physiological dysautonomia in Egr3-deficient mice. Development. 2008 Sep;135(17):2949-57. DOI:10.1242/dev.023960 | PubMed ID:18653557 | HubMed [Paper1]
  2. Gao X, Daugherty RL, and Tourtellotte WG. Regulation of low affinity neurotrophin receptor (p75(NTR)) by early growth response (Egr) transcriptional regulators. Mol Cell Neurosci. 2007 Dec;36(4):501-14. DOI:10.1016/j.mcn.2007.08.013 | PubMed ID:17916431 | HubMed [Paper2]
  3. Carter JH, Lefebvre JM, Wiest DL, and Tourtellotte WG. Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival. J Immunol. 2007 Jun 1;178(11):6796-805. DOI:10.4049/jimmunol.178.11.6796 | PubMed ID:17513727 | HubMed [Paper3]
  4. Li L, Yun SH, Keblesh J, Trommer BL, Xiong H, Radulovic J, and Tourtellotte WG. Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory. Mol Cell Neurosci. 2007 May;35(1):76-88. DOI:10.1016/j.mcn.2007.02.004 | PubMed ID:17350282 | HubMed [Paper4]
  5. Carter JH and Tourtellotte WG. Early growth response transcriptional regulators are dispensable for macrophage differentiation. J Immunol. 2007 Mar 1;178(5):3038-47. DOI:10.4049/jimmunol.178.5.3038 | PubMed ID:17312150 | HubMed [Paper5]
  6. Li L, Carter J, Gao X, Whitehead J, and Tourtellotte WG. The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors. Mol Cell Biol. 2005 Dec;25(23):10286-300. DOI:10.1128/MCB.25.23.10286-10300.2005 | PubMed ID:16287845 | HubMed [Paper6]
  7. Albert Y, Whitehead J, Eldredge L, Carter J, Gao X, and Tourtellotte WG. Transcriptional regulation of myotube fate specification and intrafusal muscle fiber morphogenesis. J Cell Biol. 2005 Apr 25;169(2):257-68. DOI:10.1083/jcb.200501156 | PubMed ID:15837802 | HubMed [Paper7]
  8. Whitehead J, Keller-Peck C, Kucera J, and Tourtellotte WG. Glial cell-line derived neurotrophic factor-dependent fusimotor neuron survival during development. Mech Dev. 2005 Jan;122(1):27-41. DOI:10.1016/j.mod.2004.09.003 | PubMed ID:15582775 | HubMed [Paper8]
  9. Chen HH, Tourtellotte WG, and Frank E. Muscle spindle-derived neurotrophin 3 regulates synaptic connectivity between muscle sensory and motor neurons. J Neurosci. 2002 May 1;22(9):3512-9. DOI:20026279 | PubMed ID:11978828 | HubMed [Paper9]
  10. Tourtellotte WG, Keller-Peck C, Milbrandt J, and Kucera J. The transcription factor Egr3 modulates sensory axon-myotube interactions during muscle spindle morphogenesis. Dev Biol. 2001 Apr 15;232(2):388-99. DOI:10.1006/dbio.2001.0202 | PubMed ID:11401400 | HubMed [Paper10]
  11. Tourtellotte WG, Nagarajan R, Bartke A, and Milbrandt J. Functional compensation by Egr4 in Egr1-dependent luteinizing hormone regulation and Leydig cell steroidogenesis. Mol Cell Biol. 2000 Jul;20(14):5261-8. DOI:10.1128/mcb.20.14.5261-5268.2000 | PubMed ID:10866682 | HubMed [Paper11]
  12. Tourtellotte WG, Nagarajan R, Auyeung A, Mueller C, and Milbrandt J. Infertility associated with incomplete spermatogenic arrest and oligozoospermia in Egr4-deficient mice. Development. 1999 Nov;126(22):5061-71. PubMed ID:10529423 | HubMed [Paper12]
  13. Tourtellotte WG and Milbrandt J. Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3. Nat Genet. 1998 Sep;20(1):87-91. DOI:10.1038/1757 | PubMed ID:9731539 | HubMed [Paper13]

All Medline abstracts: PubMed | HubMed

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