User talk:Carey Dougan

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Hello, Carey Dougan! This is a welcome message from OpenWetWare. By the way, we've announced you on the home page! You can leave messages to any OWW member by editing their User_talk pages like this one. And don't forget to personalize your User Page so that we can get to know you better! We've included some tips below to get you started.

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Endochondral Ossification

Mesenchymal stem cells (MSCs) differentiate into many generative cells during skeletal formation. One of those pathways involves MSCs differentiating into chondrocytes, which are responsible for producing and maintaining the extra-cellular matrix of cartilage. These chondrocytes deposit a cartilage model of the skeletal elements where longitudinal growth is essential, such as the limbs, phalanges, and vertebrae. Osteoblasts then replace the cartilage with bone in a process known as endochondral ossification. It is important to understand the complex interactions between the cells and signaling pathways involved in formation to be able to apply them to regeneration.