User:Yanran Li

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Contact Info

Yanran Li (an artistic interpretation)
  • Yanran Li
  • Postdoc
  • Smolke Lab, Stanford University
  • Department of Bioengineering
  • Y2E2 Building, 473 Via Ortega
  • Stanford, CA 94305-4201
  • Email me through OpenWetWare

Education

  • 2012, PhD, University of California, Los Angeles
  • 2007, BS, Nankai University
  • 2007, BE, Tianjin University

Research interests

  1. Metabolic engineering of pharmaceutically important natural products in S. cerevisiae

Publications

  1. Zhang W, Li Y, and Tang Y. Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20683-8. DOI:10.1073/pnas.0809084105 | PubMed ID:19075227 | HubMed [Paper1]
  2. Zhou H, Li Y, and Tang Y. Cyclization of aromatic polyketides from bacteria and fungi. Nat Prod Rep. 2010 Jun;27(6):839-68. DOI:10.1039/b911518h | PubMed ID:20358042 | HubMed [Paper2]
  3. Li Y, Image II, Xu W, Image I, Tang Y, and Image I. Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. J Biol Chem. 2010 Jul 23;285(30):22764-73. DOI:10.1074/jbc.M110.128504 | PubMed ID:20479000 | HubMed [Paper3]
  4. Li Y, Chooi YH, Sheng Y, Valentine JS, and Tang Y. Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase. J Am Chem Soc. 2011 Oct 5;133(39):15773-85. DOI:10.1021/ja206906d | PubMed ID:21866960 | HubMed [Paper4]
  5. Liu Q, Yao F, Chooi YH, Kang Q, Xu W, Li Y, Shao Y, Shi Y, Deng Z, Tang Y, and You D. Elucidation of Piericidin A1 biosynthetic locus revealed a thioesterase-dependent mechanism of α-pyridone ring formation. Chem Biol. 2012 Feb 24;19(2):243-53. DOI:10.1016/j.chembiol.2011.12.018 | PubMed ID:22365607 | HubMed [Paper5]
  6. Chooi YH, Wang P, Fang J, Li Y, Wu K, Wang P, and Tang Y. Discovery and characterization of a group of fungal polycyclic polyketide prenyltransferases. J Am Chem Soc. 2012 Jun 6;134(22):9428-37. DOI:10.1021/ja3028636 | PubMed ID:22590971 | HubMed [Paper6]
All Medline abstracts: PubMed | HubMed

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