I am a new member of OpenWetWare!
- Yanglong Zhu
- University Health Network, CFIBCR
- University of Toronto
- Toronto, M5G 2C1
- Email me through OpenWetWare
I am now working in the SDone Lab in University Health Network, University of Toronto. I learned about OpenWetWare from mailing list by Bioinformatics.org, and I've joined initially because I thought I might be able to contribute a bit to this open community. Now, I've been able to contribute to this open community. I wish this system improves constantly, its functionality expands steadily, the utility of this OWW becomes widely accepted and this community grows quickly.
- Year, PhD, Institute
- Year, MS, Institute
- Year, BS, Institute
I was initially trained as a paleontologist with a BSc and an MSc degree. My specialty in this field was vertebrate paleontology. Then I changed my major to molecular biology with a PhD degree. At the time I found there was a chance to pick up some bioinformatics interests and started publishing on RNA (ribozymes) structure, function and phylogenetics implications. In the meantime, I made a library of human microRNAs in a Lentivrirus vector and investigated the genetic linkage of schizophrenia. Yes, I am a wonderer always not knowing what I am doing.
Well, my present interests are:
- Cancer related genes and regulatory networks using whatever technology, arrays, deep sequencing, and other high throughput and low throughput techniques.
- Informatics tool development and knowledge discovery for any field, biased towards biomedical usage as the starting point.
- Genetic manipulation to gain control of gene expression and produce enzymes and pharmaceutical chemicals using any system, eukaryotic, prokaryotic, archean or in vitro, ex vivo ....
- Goldbeter A and Koshland DE Jr. An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6840-4.
- JACOB F and MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318-56.
leave a comment about a paper here
- Mark Ptashne. A genetic switch. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press, 2004. ISBN:0879697164