User:Timothy Ritty

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Contact Info

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  • Timothy Ritty
  • Penn State University
  • College of Medicine
  • Departments of Orthopaedics and Pathology
  • Mailcode H089
  • 500 University Drive
  • Hershey, PA, 17033, USA.
  • Email me through OpenWetWare


Education

  • Ph.D., Molecular Biology, University of Texas, Health Science Center, MD Anderson Cancer Center, Houston, TX
  • B.S., Cellular Biology, University of Kansas, Lawrence, KS

==Research interests==

  1. Metastatic Mechanisms of Osteosarcoma: We are investigating integrin mediated and matrix metalloproteinase (MMP) dependent mechanisms of osteosarcoma metastasis.
  2. Sarcoma Biomarker Identification: We are performing proteomic analysis by mass spectroscopy of sarcoma tumor samples using laser capture microscopy and tissue microarrays.
  3. Polymer Scaffolds for Cellular Attachment: We are evaluating cellular attachment to various nano- and micro-scale topologies made with the polymer parylene C.

Publications

  1. Jaishankar A, Barthelery M, Freeman WM, Salli U, Ritty TM, and Vrana KE. Human embryonic and mesenchymal stem cells express different nuclear proteomes. Stem Cells Dev. 2009 Jun;18(5):793-802. DOI:10.1089/scd.2008.0156 | PubMed ID:18821827 | HubMed [Paper1]
  2. McGowan SE, Holmes AJ, Mecham RP, and Ritty TM. Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration. Am J Respir Cell Mol Biol. 2008 Apr;38(4):435-45. DOI:10.1165/rcmb.2007-0281OC | PubMed ID:18006876 | HubMed [Paper2]
  3. Boregowda R, Paul E, White J, and Ritty TM. Bone and soft connective tissue alterations result from loss of fibrillin-2 expression. Matrix Biol. 2008 Oct;27(8):661-6. DOI:10.1016/j.matbio.2008.09.579 | PubMed ID:18838118 | HubMed [Paper3]
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All Medline abstracts: PubMed | HubMed

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